Front Cover: (Het)aryl Difluoromethyl‐Substituted β‐Alkoxyenones: Synthesis and Heterocyclizations (Eur. J. Org. Chem. 9/2020)
2020; Wiley; Volume: 2020; Issue: 9 Linguagem: Inglês
10.1002/ejoc.202000039
ISSN1434-193X
AutoresMaksym Ya. Bugera, Karen V. Tarasenko, Ivan S. Kondratov, Igor I. Gerus, Bohdan V. Vashchenko, Viktor E. Ivasyshyn, Oleksandr O. Grygorenko,
Tópico(s)Fluorine in Organic Chemistry
ResumoThe Front Cover shows (het)aryl difluoromethyl-substituted β-alkoxyenones, depicted as a bridge providing access to new areas of chemical space. In particular, heterocyclizations of these fluorinated bis-electrophiles lead to compounds bearing a difluoro–CF2–(hetero)aryl motif – promising novel chemotypes for drug discovery. Inspiration from J. J. Grandville's illustration from Un Autre Mond (H. Fournier, Paris, 1844), as well as invaluable help of Mr. Serhii Gula and Ms. Vladyslava Prykhodko with artwork preparation are appreciated. More information can be found in the Full Paper by I. S. Kondratov, O. O. Grygorenko et al.
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