MicroRNA Detection: Single Functionalized pRNA/Gold Nanoparticle for Ultrasensitive MicroRNA Detection Using Electrochemical Surface‐Enhanced Raman Spectroscopy (Adv. Sci. 3/2020)
2020; Wiley; Volume: 7; Issue: 3 Linguagem: Inglês
10.1002/advs.202070012
ISSN2198-3844
AutoresTaek Lee, Mohsen Mohammadniaei, Hui Zhang, Jinho Yoon, Hye Kyu Choi, Sijin Guo, Peixuan Guo, Jeong‐Woo Choi,
Tópico(s)RNA Interference and Gene Delivery
ResumoAdvanced ScienceVolume 7, Issue 3 2070012 Cover PictureOpen Access MicroRNA Detection: Single Functionalized pRNA/Gold Nanoparticle for Ultrasensitive MicroRNA Detection Using Electrochemical Surface-Enhanced Raman Spectroscopy (Adv. Sci. 3/2020) Taek Lee, Taek Lee College of Pharmacy, College of Medicine/Department of Physiology and Cell Biology/Dorothy M. Davis Heart and Lung Research Institute, Ohio State University, Columbus, OH, 43210 USA Department of Chemical and Biomolecular Engineering, Sogang University, 35 Baekbeom-ro, Mapo-gu, Seoul, 121-742 Republic of Korea Department of Chemical Engineering, Kwangwoon University, 20 Kwangwoon-Ro, Nowon-Gu, Seoul, 01897 Republic of KoreaSearch for more papers by this authorMohsen Mohammadniaei, Mohsen Mohammadniaei Department of Chemical and Biomolecular Engineering, Sogang University, 35 Baekbeom-ro, Mapo-gu, Seoul, 121-742 Republic of KoreaSearch for more papers by this authorHui Zhang, Hui Zhang College of Pharmacy, College of Medicine/Department of Physiology and Cell Biology/Dorothy M. Davis Heart and Lung Research Institute, Ohio State University, Columbus, OH, 43210 USASearch for more papers by this authorJinho Yoon, Jinho Yoon Department of Chemical and Biomolecular Engineering, Sogang University, 35 Baekbeom-ro, Mapo-gu, Seoul, 121-742 Republic of KoreaSearch for more papers by this authorHye Kyu Choi, Hye Kyu Choi Department of Chemical and Biomolecular Engineering, Sogang University, 35 Baekbeom-ro, Mapo-gu, Seoul, 121-742 Republic of KoreaSearch for more papers by this authorSijin Guo, Sijin Guo College of Pharmacy, College of Medicine/Department of Physiology and Cell Biology/Dorothy M. Davis Heart and Lung Research Institute, Ohio State University, Columbus, OH, 43210 USASearch for more papers by this authorPeixuan Guo, Peixuan Guo College of Pharmacy, College of Medicine/Department of Physiology and Cell Biology/Dorothy M. Davis Heart and Lung Research Institute, Ohio State University, Columbus, OH, 43210 USASearch for more papers by this authorJeong-Woo Choi, Jeong-Woo Choi Department of Chemical and Biomolecular Engineering, Sogang University, 35 Baekbeom-ro, Mapo-gu, Seoul, 121-742 Republic of KoreaSearch for more papers by this author Taek Lee, Taek Lee College of Pharmacy, College of Medicine/Department of Physiology and Cell Biology/Dorothy M. Davis Heart and Lung Research Institute, Ohio State University, Columbus, OH, 43210 USA Department of Chemical and Biomolecular Engineering, Sogang University, 35 Baekbeom-ro, Mapo-gu, Seoul, 121-742 Republic of Korea Department of Chemical Engineering, Kwangwoon University, 20 Kwangwoon-Ro, Nowon-Gu, Seoul, 01897 Republic of KoreaSearch for more papers by this authorMohsen Mohammadniaei, Mohsen Mohammadniaei Department of Chemical and Biomolecular Engineering, Sogang University, 35 Baekbeom-ro, Mapo-gu, Seoul, 121-742 Republic of KoreaSearch for more papers by this authorHui Zhang, Hui Zhang College of Pharmacy, College of Medicine/Department of Physiology and Cell Biology/Dorothy M. Davis Heart and Lung Research Institute, Ohio State University, Columbus, OH, 43210 USASearch for more papers by this authorJinho Yoon, Jinho Yoon Department of Chemical and Biomolecular Engineering, Sogang University, 35 Baekbeom-ro, Mapo-gu, Seoul, 121-742 Republic of KoreaSearch for more papers by this authorHye Kyu Choi, Hye Kyu Choi Department of Chemical and Biomolecular Engineering, Sogang University, 35 Baekbeom-ro, Mapo-gu, Seoul, 121-742 Republic of KoreaSearch for more papers by this authorSijin Guo, Sijin Guo College of Pharmacy, College of Medicine/Department of Physiology and Cell Biology/Dorothy M. Davis Heart and Lung Research Institute, Ohio State University, Columbus, OH, 43210 USASearch for more papers by this authorPeixuan Guo, Peixuan Guo College of Pharmacy, College of Medicine/Department of Physiology and Cell Biology/Dorothy M. Davis Heart and Lung Research Institute, Ohio State University, Columbus, OH, 43210 USASearch for more papers by this authorJeong-Woo Choi, Jeong-Woo Choi Department of Chemical and Biomolecular Engineering, Sogang University, 35 Baekbeom-ro, Mapo-gu, Seoul, 121-742 Republic of KoreaSearch for more papers by this author First published: 05 February 2020 https://doi.org/10.1002/advs.202070012Citations: 10AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat Graphical Abstract In article number 1902477, Peixuan Guo, Jeong-Woo Choi, and co-workers fabricate monofunctionalized gold nanoparticles (AuNPs) with a single copy of an RNA three-way junction (3WJ) motif for application in ultra-sensitive miRNA biosensing using electrochemical surface-enhanced Raman spectroscopy (EC-SERS). In the presence of miRNA-155, miRNA-155 displaces the 3WJ structure and it results in a remarkable increase in the electrochemical and SERS signals. Citing Literature Volume7, Issue3February 5, 20202070012 RelatedInformation
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