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Incidence of diabetes mellitus in Spain as results of the nation-wide cohort di@bet.es study

2020; Nature Portfolio; Volume: 10; Issue: 1 Linguagem: Inglês

10.1038/s41598-020-59643-7

2045-2322

Gemma Rojo‐Martínez, Sergio Valdés, Federico Soriguer, Joan Vendrell, Inés Urrutia, Vidal Pérez, Emilio Ortega, P. Ocón, Eduard Montanya, Edelmiro Menéndez Torre, Ana Lago‐Sampedro, T. González- Frutos, Ramón Gomis, Albert Goday, Sara García‐Serrano, Eva García‐Escobar, José Luis Galán–García, Conxa Castell, Rocío Badía-Guillén, Gabriel Aguilera‐Venegas, J. Girbés, Sonia Gaztambide, Josep Franch‐Nadal, Elías Delgado, Felipe J. Chaves, Luís Castaño, Alfonso L. Calle‐Pascual,

Nutritional Studies and Diet

Our aim was to determine the incidence of type 2 diabetes mellitus in a nation-wide population based cohort from Spain (di@bet.es study). The target was the Spanish population. In total 5072 people older than 18 years,were randomly selected from all over Spain). Socio-demographic and clinical data, survey on habits (physical activity and food consumption) and weight, height, waist, hip and blood pressure were recorder. A fasting blood draw and an oral glucose tolerance test were performed. Determinations of serum glucose were made. In the follow-up the same variables were collected and HbA1c was determined. A total of 2408 subjects participated in the follow-up. In total, 154 people developed diabetes (6.4% cumulative incidence in 7.5 years of follow-up). The incidence of diabetes adjusted for the structure of age and sex of the Spanish population was 11.6 cases/1000 person-years (IC95% = 11.1-12.1). The incidence of known diabetes was 3.7 cases/1000 person-years (IC95% = 2.8-4.6). The main risk factors for developing diabetes were the presence of prediabetes in cross-sectional study, age, male sex, obesity, central obesity, increase in weight, and family history of diabetes. This work provides data about population-based incidence rates of diabetes and associated risk factors in a nation-wide cohort of Spanish population.