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Cartilage repair mediated by thermosensitive photocrosslinkable TGFβ1-loaded GM-HPCH via immunomodulating macrophages, recruiting MSCs and promoting chondrogenesis

2020; Ivyspring International Publisher; Volume: 10; Issue: 6 Linguagem: Inglês

10.7150/thno.41622

1838-7640

Xiongfa Ji, Zehua Lei, Meng Yuan, Hao Zhu, Xi Yuan, Wenbin Liu, Hongxu Pu, Jiawei Jiang, Yu Zhang, Xulin Jiang, Jun Xiao,

Silk-based biomaterials and applications

Repairing cartilage defects using thermosensitive hydrogels is an attractive treatment strategy, but the poor mechanical properties and limited understanding of the interactions between hydrogels and cells limit their application.