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Immunohistochemical evidence of canine morbillivirus (canine distemper) infection in coatis ( Nasua nasua ) from Southern Brazil
2020; Wiley; Volume: 67; Issue: S2 Linguagem: Inglês
10.1111/tbed.13456
ISSN1865-1682
AutoresMariana de Mello Zanim Michelazzo, Thalita Evani Silva de Oliveira, Nayara Emily Viana, Wanderlei de Moraes, Zalmir Silvino Cubas, Selwyn Arlington Headley,
Tópico(s)Vector-borne infectious diseases
ResumoTransboundary and Emerging DiseasesVolume 67, Issue S2 p. 178-184 SUPPLEMENT ARTICLE Immunohistochemical evidence of canine morbillivirus (canine distemper) infection in coatis (Nasua nasua) from Southern Brazil Mariana de Mello Zanim Michelazzo, Mariana de Mello Zanim Michelazzo orcid.org/0000-0002-7324-4351 Laboratory of Animal Pathology, Department of Veterinary Preventive Medicine, Universidade Estadual de Londrina, Paraná, Brazil Part of the MSc dissertation of the first author (MMZM).Search for more papers by this authorThalita Evani Silva de Oliveira, Thalita Evani Silva de Oliveira orcid.org/0000-0001-6894-9253 Laboratory of Animal Pathology, Department of Veterinary Preventive Medicine, Universidade Estadual de Londrina, Paraná, BrazilSearch for more papers by this authorNayara Emily Viana, Nayara Emily Viana orcid.org/0000-0002-4759-557X Laboratory of Animal Pathology, Department of Veterinary Preventive Medicine, Universidade Estadual de Londrina, Paraná, BrazilSearch for more papers by this authorWanderlei de Moraes, Wanderlei de Moraes Bela Vista Sanctuary, Itaipu Binacional, Foz do Iguaçu, BrazilSearch for more papers by this authorZalmir Silvino Cubas, Zalmir Silvino Cubas Bela Vista Sanctuary, Itaipu Binacional, Foz do Iguaçu, BrazilSearch for more papers by this authorSelwyn Arlington Headley, Corresponding Author Selwyn Arlington Headley selwyn.headley@uel.br orcid.org/0000-0002-1614-0185 Laboratory of Animal Pathology, Department of Veterinary Preventive Medicine, Universidade Estadual de Londrina, Paraná, Brazil Correspondence Selwyn Arlington Headley, Laboratory of Animal Pathology, Department of Veterinary Preventive Medicine, Universidade Estadual de Londrina, Rodovia Celso Garcia Cid, PR 445 Km 380, Campus Universitário, PO Box 10.011, 86057-970, Londrina, Paraná, Brazil. Email: selwyn.headley@uel.brSearch for more papers by this author Mariana de Mello Zanim Michelazzo, Mariana de Mello Zanim Michelazzo orcid.org/0000-0002-7324-4351 Laboratory of Animal Pathology, Department of Veterinary Preventive Medicine, Universidade Estadual de Londrina, Paraná, Brazil Part of the MSc dissertation of the first author (MMZM).Search for more papers by this authorThalita Evani Silva de Oliveira, Thalita Evani Silva de Oliveira orcid.org/0000-0001-6894-9253 Laboratory of Animal Pathology, Department of Veterinary Preventive Medicine, Universidade Estadual de Londrina, Paraná, BrazilSearch for more papers by this authorNayara Emily Viana, Nayara Emily Viana orcid.org/0000-0002-4759-557X Laboratory of Animal Pathology, Department of Veterinary Preventive Medicine, Universidade Estadual de Londrina, Paraná, BrazilSearch for more papers by this authorWanderlei de Moraes, Wanderlei de Moraes Bela Vista Sanctuary, Itaipu Binacional, Foz do Iguaçu, BrazilSearch for more papers by this authorZalmir Silvino Cubas, Zalmir Silvino Cubas Bela Vista Sanctuary, Itaipu Binacional, Foz do Iguaçu, BrazilSearch for more papers by this authorSelwyn Arlington Headley, Corresponding Author Selwyn Arlington Headley selwyn.headley@uel.br orcid.org/0000-0002-1614-0185 Laboratory of Animal Pathology, Department of Veterinary Preventive Medicine, Universidade Estadual de Londrina, Paraná, Brazil Correspondence Selwyn Arlington Headley, Laboratory of Animal Pathology, Department of Veterinary Preventive Medicine, Universidade Estadual de Londrina, Rodovia Celso Garcia Cid, PR 445 Km 380, Campus Universitário, PO Box 10.011, 86057-970, Londrina, Paraná, Brazil. Email: selwyn.headley@uel.brSearch for more papers by this author First published: 20 February 2020 https://doi.org/10.1111/tbed.13456Citations: 3 Funding information Conselho Nacional de Desenvolvimento Científico e Tecnológico; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior. Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat Abstract The pathological and immunohistochemical (IHC) findings associated with infection due to canine morbilivírus (canine distemper virus, CDV) are described in coatis (Nasua nasua). Tissue fragments of coatis (n = 13) that died at the Bela Vista Sanctuary, Paraná, Southern Brazil, were routinely processed for histopathology to identify the main histopathologic patterns as compared to that of the domestic dog. Selected formalin-fixed paraffin-embedded (FFPE) tissue fragments of the lungs, liver, urinary bladder and small intestine were used in IHC assays designed to identify the antigens of CDV, canine adenovirus (CAdV-1 and CAdV-2) and canine parvovirus type 2 (CPV-2). The main histopathologic patterns identified were interstitial pneumonia (n = 9), interstitial nephritis (n = 6), atrophic enteritis (n = 4) and ballooning degeneration of the uroepithelium (n = 3). Positive immunolabelling for intralesional antigens of CDV was identified in the lung with interstitial pneumonia (n = 3), in the intestine (n = 2) and in the degenerated epithelium of the urinary bladder (n = 2). Antigens of CPV-2, CAdV-1 and CAdV-2 were not identified in any FFPE tissue sections evaluated. These findings indicate that these wild carnivores were infected by a viral disease pathogen common to the domestic dog and develop similar histopathologic findings. Collectively, these findings suggest that these coatis were infected by CDV and can serve as a potential host for this infectious disease pathogen. CONFLICT OF INTEREST The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article. Citing Literature Volume67, IssueS2Special Issue: International Congress on Tropical Veterinary Medicine. 2nd Joint AITVM-STVM Meeting. Animal Health in the Tropics: Building the puzzle from research to application, 23rd September 2018, Buenos Aires, ArgentinaJuly 2020Pages 178-184 RelatedInformation
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