Artigo Acesso aberto Revisado por pares

Distinct Mechanisms of Dissemination of NDM-1 Metallo-β-Lactamase in Acinetobacter Species in Argentina

2020; American Society for Microbiology; Volume: 64; Issue: 5 Linguagem: Inglês

10.1128/aac.00324-20

ISSN

1098-6596

Autores

Mark D. Adams, Fernando Pasterán, Germán M. Traglia, Jasmine Martinez, Fanny Huang, Christine Liu, Jennifer S. Fernandez, Carolina López, Lisandro J. González, Ezequiel Albornoz, Alejandra Corso, Alejandro J. Vila, Robert A. Bonomo, María Soledad Ramirez,

Tópico(s)

Vibrio bacteria research studies

Resumo

A 4-year surveillance of carbapenem-resistant Acinetobacter spp. isolates in Argentina identified 40 strains carrying blaNDM-1 Genome sequencing revealed that most were Acinetobacter baumannii, whereas seven represented other Acinetobacter spp. The A. baumannii genomes were closely related, suggesting recent spread. blaNDM-1 was located in the chromosome of A. baumannii strains and on a plasmid in non-A. baumannii strains. A resistance gene island carrying blaPER-7 and other resistance determinants was found on a plasmid in some A. baumannii strains.

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