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A year in review in Minerva Anestesiologica 2019. Anesthesia, analgesia, and perioperative medicine

2020; Edizioni Minerva Medica; Volume: 86; Issue: 2 Linguagem: Inglês

10.23736/s0375-9393.20.14424-9

1827-1596

Franco Cavaliere, Massimo Allegri, Alparslan Apan, Edoardo Calderini, Massimiliano Carassiti, Edmond Cohen, Flaminia Coluzzi, Pierangelo Di Marco, Olivier Langeron, Marco Rossi, Peter M. Spieth, David Turnbull,

Airway Management and Intubation Techniques

General anesthesiai nnovations in anesthesia are probably less fre- quent than in other fields, but new techniques to administer old drugs and the research of secure and reliable monitoring devices have animated the debate in the last year. 1, 2Drug association is a common practice, looking for positive effects in terms of efficacy and reduction of total doses.the combination of hypnotics like propofol and analgesics like sufentanil can improve anesthesia induction and offer stable maintenance during surgery. 3a study by Weber and Prasser on 60 patients who underwent sufentanil and propofol target-controlled anesthesia (tci) offered new insights on the synergism between the two drugs 4 and opened to the possibility of tci models based on drug interactions. 5However, even a tci model that considers the interaction between hypnotics and analgesics are subject to individual variability.closed-loop anesthesia is aimed at overcoming this problem.an elegant randomized trial by reboso et al. investigated the feasibility of adding a predictor to a controller in a closed-loop system to reach the desired hypnotic effect of Propofol earlier. 6the combined software showed better performance than the operator's adjustments, reducing the number of anesthetist interventions.Despite their long history of use, volatile anesthetics are still a topic of interest. 7in January, Ma published an exhaustive Pros-cons article on Xenon focused not only on pharmacodynamic and pharmacokinetic properties but also on collateral effects, such as the cytoprotective one. 8Pros included rapid induction and fast recovery