Portal de Periódicos da CAPES

Supercritical CO2 Extraction and Identification of Ginsenosides in Russian and North Korean Ginseng by HPLC with Tandem Mass Spectrometry

2020; Multidisciplinary Digital Publishing Institute; Volume: 25; Issue: 6 Linguagem: Inglês

10.3390/molecules25061407

1433-1373

Mayya P. Razgonova, Alexander M. Zakharenko, Tai‐Sun Shin, Gyuhwa Chung, Kirill S. Golokhvast,

Pharmacological Effects of Natural Compounds

Ginseng roots, Panax ginseng C.A. Meyer, obtained from cultivated ginseng grown in the Kaesong province (North Korea) and Primorye (Russia) were extracted using the supercritical CO2 extraction method. The extracts were subsequently analyzed by high-performance liquid chromatography with tandem mass spectrometry identification. The results showed the spectral peaks of typical ginsenosides with some other minor groups, and major differences were observed between the spectra of the two ginseng samples. The use of a pressure of 400 bar and higher allowed an increase in the yield of ginsenosides in comparison with similar previous studies.