A human monoclonal antibody blocking SARS-CoV-2 infection
2020; Cold Spring Harbor Laboratory; Linguagem: Inglês
10.1101/2020.03.11.987958
AutoresChunyan Wang, Wentao Li, Dubravka Drabek, Nisreen M.A. Okba, Rien van Haperen, Albert D. M. E. Osterhaus, Frank J. M. van Kuppeveld, Bart L. Haagmans, Frank Grosveld, Berend‐Jan Bosch,
Tópico(s)Immunotherapy and Immune Responses
ResumoAbstract The emergence of the novel human coronavirus SARS-CoV-2 in Wuhan, China has caused a worldwide epidemic of respiratory disease (COVID-19). Vaccines and targeted therapeutics for treatment of this disease are currently lacking. Here we report a human monoclonal antibody that neutralizes SARS-CoV-2 (and SARS-CoV). This cross-neutralizing antibody targets a communal epitope on these viruses and offers potential for prevention and treatment of COVID-19.
Referência(s)