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Investigation of three clusters of COVID-19 in Singapore: implications for surveillance and response measures

2020; Elsevier BV; Volume: 395; Issue: 10229 Linguagem: Inglês

10.1016/s0140-6736(20)30528-6

1474-547X

Rachael Pung, Calvin J. Chiew, Barnaby Edward Young, Sarah Chin, Mark Chen, Hannah Clapham, Alex R. Cook, Sebastian Maurer‐Stroh, Matthias Paul HS Toh, Cuiqin Poh, Mabel Sheau Fong Low, Joshua Lum, Valerie T J Koh, Tze Minn Mak, Lin Cui, Raymond Lin, Derrick Heng, Yee‐Sin Leo, David Chien Lye, Vernon J. M. Lee, Kai‐Qian Kam, Shirin Kalimuddin, Seow Yen Tan, Jiashen Loh, Koh Cheng Thoon, Shawn Vasoo, Wei Xin Khong, Nur-Afidah Md Suhaimi, Sherlynn JH Chan, Emma Zhang, Olivia Seen Huey Oh, Albert Ty, Charlene Tow, Yi Xian Chua, Wei Liang Chaw, Yixiang Ng, Farid Abdul-Rahman, Shafiq Sahib, Zheng Zhao, Cheryl Tang, Constance Low, Ee Hui Goh, Georgina Lim, Yanan Hou, Imran Roshan, James Tan, Kelly Foo, Khine Nandar, Lalitha Kurupatham, Pei Pei Chan, P. Ernest Raj, Yijun Lin, Zubaidah Said, Anne Lee, Cherie See, Jessey Markose, Joanna Weihui Tan, Guanhao Chan, Wanhan See, Xinyi Peh, Vincent Cai, Wen Kai Chen, Zongbin Li, Roy Jiunn Jye Soo, Angela Chow, Wycliffe Enli Wei, Aysha Farwin, Ang Li,

COVID-19 and Mental Health

Three clusters of coronavirus disease 2019 (COVID-19) linked to a tour group from China, a company conference, and a church were identified in Singapore in February, 2020.We gathered epidemiological and clinical data from individuals with confirmed COVID-19, via interviews and inpatient medical records, and we did field investigations to assess interactions and possible modes of transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Open source reports were obtained for overseas cases. We reported the median (IQR) incubation period of SARS-CoV-2.As of Feb 15, 2020, 36 cases of COVID-19 were linked epidemiologically to the first three clusters of circumscribed local transmission in Singapore. 425 close contacts were quarantined. Direct or prolonged close contact was reported among affected individuals, although indirect transmission (eg, via fomites and shared food) could not be excluded. The median incubation period of SARS-CoV-2 was 4 days (IQR 3-6). The serial interval between transmission pairs ranged between 3 days and 8 days.SARS-CoV-2 is transmissible in community settings, and local clusters of COVID-19 are expected in countries with high travel volume from China before the lockdown of Wuhan and institution of travel restrictions. Enhanced surveillance and contact tracing is essential to minimise the risk of widespread transmission in the community.None.