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COVID-19: A promising cure for the global panic

2020; Elsevier BV; Volume: 725; Linguagem: Inglês

10.1016/j.scitotenv.2020.138277

1879-1026

Balachandar Vellingiri, Kaavya Jayaramayya, Mahalaxmi Iyer, Arul Narayanasamy, Vivekanandhan Govindasamy, Bupesh Giridharan, Singaravelu Ganesan, Anila Venugopal, Dhivya Venkatesan, Harsha Ganesan, Kamarajan Rajagopalan, Pattanathu Rahman, Ssang‐Goo Cho, Nachimuthu Senthil Kumar, Mohana Devi Subramaniam,

COVID-19 Clinical Research Studies

The novel Coronavirus disease 2019 (COVID-19) is caused by SARS-CoV-2, which is the causative agent of a potentially fatal disease that is of great global public health concern. The outbreak of COVID-19 is wreaking havoc worldwide due to inadequate risk assessment regarding the urgency of the situation. The COVID-19 pandemic has entered a dangerous new phase. When compared with SARS and MERS, COVID-19 has spread more rapidly, due to increased globalization and adaptation of the virus in every environment. Slowing the spread of the COVID-19 cases will significantly reduce the strain on the healthcare system of the country by limiting the number of people who are severely sick by COVID-19 and need hospital care. Hence, the recent outburst of COVID-19 highlights an urgent need for therapeutics targeting SARS-CoV-2. Here, we have discussed the structure of virus; varying symptoms among COVID-19, SARS, MERS and common flu; the probable mechanism behind the infection and its immune response. Further, the current treatment options, drugs available, ongoing trials and recent diagnostics for COVID-19 have been discussed. We suggest traditional Indian medicinal plants as possible novel therapeutic approaches, exclusively targeting SARS-CoV-2 and its pathways.