A caged E3 ligase ligand for PROTAC-mediated protein degradation with light
2020; Royal Society of Chemistry; Volume: 56; Issue: 41 Linguagem: Inglês
10.1039/d0cc00523a
ISSN1364-548X
AutoresCyrille S. Kounde, Maria M. Shchepinova, Charlie N. Saunders, Marcel Muelbaier, M.D. Rackham, John D. Harling, Edward W. Tate,
Tópico(s)Peptidase Inhibition and Analysis
ResumoCaging of a widely used Von Hippel Lindau E3 ligase ligand for targeted protein degradation with PROTACs allows light-activated proteolysis.
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