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BIBTEX RIS

Transferable Resistance Gene optrA in Enterococcus faecalis from Swine in Brazil

2020; American Society for Microbiology; Volume: 64; Issue: 6 Linguagem: Inglês

10.1128/aac.00142-20

ISSN

1098-6596

Autores

Lara Mendes de Almeida, François Lebreton, Anthony O. Gaca, Paulo J. M. Bispo, José T. Saavedra, Rodrigo N. Calumby, Luciano Aparecido Meireles Grillo, Ticiano Gomes do Nascimento, Pedro H. Filsner, Andréa Micke Moreno, Michael S. Gilmore,

Tópico(s)

Microbial infections and disease research

Resumo

OptrA is an ATP-binding cassette (ABC)-F protein that confers resistance to oxazolidinones and phenicols and can be either plasmid-encoded or chromosomally encoded. Here, we isolated 13 Enterococcus faecalis strains possessing a linezolid MIC of ≥4 mg/liter from nursery pigs in swine herds located across Brazil. Genome sequence comparison showed that these strains possess optrA in different genetic contexts occurring in 5 different E. faecalis sequence type backgrounds.

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