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Clofazimine for Treatment of Cryptosporidiosis in Human Immunodeficiency Virus Infected Adults: An Experimental Medicine, Randomized, Double-blind, Placebo-controlled Phase 2a Trial

2020; Oxford University Press; Volume: 73; Issue: 2 Linguagem: Inglês

10.1093/cid/ciaa421

1537-6591

Pui‐Ying Iroh Tam, Samuel L.M. Arnold, Lynn K. Barrett, C R Chen, Tom Conrad, Elaine Douglas, Melita A. Gordon, Donald Hebert, Marc Henrion, Dave Hermann, Brandon Hollingsworth, Eric R. Houpt, Khuzwayo C. Jere, R. Lindblad, Melissa S. Love, Lumbani Makhaza, Case W. McNamara, Wilfred Nedi, James Nyirenda, Darwin J. Operario, Jacob Phulusa, Gerald V. Quinnan, L A Sawyer, Herbert Thole, Neema Toto, Allison Winter, Wesley C. Van Voorhis,

Pediatric health and respiratory diseases

We evaluated the efficacy, pharmacokinetics (PK), and safety of clofazimine (CFZ) in patients living with human immunodeficiency virus (HIV) with cryptosporidiosis.