The Epidemiological, Clinical, Biological and Morphological Characteristics of Primitive Liver Cancers in Bangui
2020; Scientific Research Publishing; Volume: 10; Issue: 04 Linguagem: Inglês
10.4236/ojgas.2020.104010
ISSN2163-9469
AutoresSerges Magloire Camengo Police, Georges Service, Nathalie Philomène Boua-Akélélo, Diane N’guilé, Benoît Elowa, Timothée Mobima, Francky Kouandogui Bangué, Eveline Mofini, Yangba Kalebanga Armelo Thibaut, Bernard Bessanguem, Boniface Koffi,
Tópico(s)Hepatitis B Virus Studies
ResumoObjective: To describe the epidemiological, clinical, biological and morphological aspects of primary liver cancer (PLC).Patients and Methods: We conducted a 38-month cross-sectional study in the Department of hepatogastroenterology and Internal Medicine "Amitié Sino-Centrafraine" University Hospital Center in Bangui.Included in the study were all patients with a diagnosis of PLC.The PLC's diagnostic arguments were the large tumor liver associated or not with the elevation of alpha-fetoprotein, the heteronodular liver hypervascularized on abdominal ultrasound.Data analysis was done using Epi Info 3.5.1 software.Results: We collected 115 cases of CPF among 2410 hospitalized patients (4.7%).There were 86 men and 29 women (sex ratio: 2.9).The average age was 50 years old.The main risk factors were alcohol consumption (72.2%) and chronic hepatitis B infection (67.4%).Frequent clinical signs were pain in the right hypochondrium and/or epigastric (93.86%), large tumor liver under examination (91.3%), weight loss (74.78%).The serum alpha-fetoprotein concentration was ≥ 400 ng/ml in 73% of the cases.The abdominal ultrasound found a heteronodular liver in all patients.The nodules were multiple hyperechoic in 66.1% of the cases.According to the Child-Pugh classification, the patients were classified as B (49.5%) and C
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