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Detection of SARS-CoV-2 RNA and Antibodies in Diverse Samples: Protocol to Validate the Sufficiency of Provider-Observed, Home-Collected Blood, Saliva, and Oropharyngeal Samples

2020; JMIR Publications; Volume: 6; Issue: 2 Linguagem: Inglês

10.2196/19054

2369-2960

Patrick S. Sullivan, Charles Sailey, Jodie L. Guest, Jeannette Guarner, Colleen F. Kelley, Aaron J. Siegler, Mariah Valentine-Graves, Laura Gravens, Carlos del Rı́o, Travis Sanchez,

COVID-19 diagnosis using AI

The response in the United States to the coronavirus disease (COVID-19) pandemic has been hampered by a lack of aggressive testing for the infection. Testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cornerstone of an effective public health response. However, efforts to test have been hampered by limited reagents, limitations in the availability of swabs used for the collection of nasopharyngeal swab (NPS) specimens, limitations in personal protective equipment (PPE) for health care providers collecting the NPS specimens, and limitations in viral transport media for transporting the specimens. Therefore, more flexible options for screening for SARS-CoV-2 RNA and serologic responses are critical to inform clinical and public health responses.