THE OSTEOBLAST
1956; Elsevier BV; Linguagem: Inglês
10.1016/b978-1-4832-3286-7.50011-7
Autores Tópico(s)Bone and Dental Protein Studies
ResumoPublisher Summary The typical osteoblast, despite its unique combination of cytological and cytochemical features, is but a temporary modification, or modulation, of a series of mutually transformable connective tissue cells resident in and around a bone within the confines of the fibrous periosteum, including the osteocyte, osteoclast, marrow reticulum cell, flattened resting osteoblast, spindle cell, and chondroblast as alternative forms. These cell types belong to a race of connective tissue cells differentiable from other connective tissue cells resident outside the skeletal territories by the ease with which they can undergo transformation into osteoblasts. In other words, they constitute a specific race of potentially osteogenetic cells. The situation of osteoblasts relative to sites of active bone formation and their highly specialized morphology and cytochemistry indicate that they have an essential role to play in bone formation, including the production of collagen and alkaline phosphatase, and possibly of organic phosphate substrates and mucopolysaccharides.
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