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COVID-19 Testing, Epidemic Features, Hospital Outcomes, and Household Prevalence, New York State—March 2020

2020; Oxford University Press; Volume: 71; Issue: 8 Linguagem: Inglês

10.1093/cid/ciaa549

1537-6591

Eli S. Rosenberg, Elizabeth Dufort, Debra Blog, Eric W. Hall, Dina Hoefer, Bryon Backenson, Alison Muse, James Kirkwood, Kirsten St. George, David R. Holtgräve, Brad Hutton, Howard A. Zucker, Madhu Anand, Alison Kaufman, Daniel Kuhles, Angie Maxted, Alexandra Newman, W Pulver, Lou Smith, Jamie Sommer, Jennifer White, Amy B. Dean, Victoria Derbyshire, Christina Egan, Meghan Fuschino, Sara B. Griesemer, Rene Hull, Daryl M. Lamson, Jennifer Laplante, Kathleen A. McDonough, Kara Mitchell, Kimberlee A. Musser, Elizabeth Nazarian, Michael Popowich, Jill Taylor, Anne C. Walsh, Sherlita Amler, Ada Huang, Renee Recchia, Elizabeth Whalen, Elizabeth Lewis, Cynthia Friedman, S. Carrera, Lawrence Eisenstein, Ann DeSimone, Johanne E. Morne, Megan Mueller Johnson, Kristen Navarette, Jessica Kumar, Stephanie Ostrowski, Adrienne Mazeau, Sally Dreslin, Nora Yates, Danielle Greene, Eugene Heslin, Emily Lutterloh, Elizabeth M. Rosenthal, Meredith A. Barranco, Madhu Anand, Alison Kaufman, Daniel Kuhles, Angie Maxted, Alexandra Newman, W Pulver, Lou Smith, Jamie Sommer, Jennifer White, Amy B. Dean, Victoria Derbyshire, Christina Egan, Meghan Fuschino, Sara B. Griesemer, Rene Hull, Daryl M. Lamson, Jennifer Laplante, Kathleen A. McDonough, Kara Mitchell, Kimberlee A. Musser, Elizabeth Nazarian, Michael Popowich, Jill Taylor, Anne C. Walsh, Sherlita Amler, Ada Huang, Renee Recchia, Elizabeth Whalen, Elizabeth Lewis, Cynthia Friedman, S. Carrera, Lawrence Eisenstein, Ann DeSimone, Johanne E. Morne, Megan Mueller Johnson, Kristen Navarette, Jessica Kumar, Stephanie Ostrowski, Adrienne Mazeau, Sally Dreslin, Nora Yates, Danielle Greene, Eugene Heslin, Emily Lutterloh, Elizabeth M. Rosenthal, Meredith A. Barranco,

COVID-19 epidemiological studies

Abstract Background The US’ coronavirus disease 2019 (COVID-19) epidemic has grown extensively since February 2020, with substantial associated hospitalizations and mortality; New York State has emerged as the national epicenter. We report on the extent of testing and test results during the month of March in New York State, along with risk factors, outcomes, and household prevalence among initial cases subject to in-depth investigations. Methods Specimen collection for COVID-19 testing was conducted in healthcare settings, community-based collection sites, and by home testing teams. Information on demographics, risk factors, and hospital outcomes of cases was obtained through epidemiological investigations and an electronic medical records match, and summarized descriptively. Active testing of initial case’s households enabled estimation of household prevalence. Results During March in New York State, outside of New York City, a total of 47 326 persons tested positive for severe acute respiratory syndrome coronavirus 2, out of 141 495 tests (33% test-positive), with the highest number of cases located in the metropolitan region counties. Among 229 initial cases diagnosed through 12 March, by 30 March 13% were hospitalized and 2% died. Testing conducted among 498 members of these case’s households found prevalent infection among 57%, excluding first-reported cases 38%. In these homes, we found a significant age gradient in prevalence, from 23% among those < 5 years to 68% among those ≥ 65 years (P < .0001). Conclusions New York State faced a substantial and increasing COVID-19 outbreak during March 2020. The earliest cases had high levels of infection in their households and by the end of the month, the risks of hospitalization and death were high.