Artigo Acesso aberto Revisado por pares

A distinct class of plant and animal viral proteins that disrupt mitosis by directly interrupting the mitotic entry switch Wee1-Cdc25-Cdk1

2020; American Association for the Advancement of Science; Volume: 6; Issue: 20 Linguagem: Inglês

10.1126/sciadv.aba3418

ISSN

2375-2548

Autores

Huaibing Jin, Z Du, Yanjing Zhang, Judit Antal, Zongliang Xia, Yan Wang, Yang Gao, Xiaoge Zhao, Xinyun Han, Yanjun Cheng, Qian‐Hua Shen, Kunpu Zhang, Robert Elder, Zsigmond Benkő, Csaba Fenyvuesvolgyi, Ge Li, Dionne Rebello, Jing Li, Shilai Bao, Yuqi Zhao, Daowen Wang,

Tópico(s)

Plant Parasitism and Resistance

Resumo

Many animal viral proteins, e.g., Vpr of HIV-1, disrupt host mitosis by directly interrupting the mitotic entry switch Wee1-Cdc25-Cdk1. However, it is unknown whether plant viruses may use this mechanism in their pathogenesis. Here, we report that the 17K protein, encoded by barley yellow dwarf viruses and related poleroviruses, delays G

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