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Cystatin C as an indicator of renal damage in pre-eclampsia

2020; Informa; Volume: 39; Issue: 3 Linguagem: Inglês

10.1080/10641955.2020.1766488

1525-6065

Hellen Cássia Dos Santos Gomes, Antônio Carlos Vieira Cabral, Sílvia Passos Andrade, Henrique Vítor Leite, Patrícia Gonçalves Teixeira, Paula Peixoto Campos, Jaqueline Amorim Arantes Gomes,

Renal and Vascular Pathologies

Objective To assess the predictive abilities of serum and urinary cystatin C levels for glomerular lesions in pregnant women with pre-eclampsia.Methods In this study, kidney function markers were compared between38 pregnant women with pre-eclampsia and 22 healthy pregnant women.Results The serum and urine levels of cystatin C and urea were significantly higher in the pre-eclampsia group than in the control group. Receiver operating characteristic curve analysis demonstrated that the serum cystatin C level (91.7%) had a superior diagnostic accuracy for pre-eclampsia than the other markers.Conclusion Serum cystatin C level maybe a significant marker of pre-eclampsia.