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BIBTEX RIS

The immunoregulatory function of polyphenols: implications in cancer immunity

2020; Elsevier BV; Volume: 85; Linguagem: Inglês

10.1016/j.jnutbio.2020.108428

1873-4847

José Tarcísio Giffoni de Carvalho, Débora da Silva Baldivia, David Tsuyoshi Hiramatsu de Castro, Helder Freitas dos Santos, Cintia Miranda dos Santos, Alex Santos Oliveira, Tamaeh Monteiro‐Alfredo, Kellen Natalice Vilharva, Kely de Picoli Souza, Edson Lucas dos Santos,

Phytochemicals and Antioxidant Activities

Polyphenols have demonstrated several potential biological activities, notably antitumoral activity dependent on immune function. In the present review, we describe studies that investigated antitumor immune responses influenced by polyphenols and the mechanisms by which polyphenols improve the immune response. We also discuss the limitations in related areas, especially unexplored areas of research, and next steps required to develop a therapeutic approach utilizing polyphenols in oncology.