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Neurological complications in patients with SARS-CoV-2 infection: a systematic review

2020; Thieme Medical Publishers (Germany); Volume: 78; Issue: 5 Linguagem: Inglês

10.1590/0004-282x20200051

1678-4227

Renato P. Munhoz, José Luiz Pedroso, Fábio A. Nascimento, Sérgio Monteiro de Almeida, Orlando Graziani Póvoas Barsottini, Francisco Cardoso, Hélio Afonso Ghizoni Teive,

COVID-19 and Mental Health

ABSTRACT Background: As the COVID-19 pandemic unfolds worldwide, different forms of reports have described its neurologic manifestations. Objective: To review the literature on neurological complications of SARS-CoV-2 infection. Methods: Literature search performed following systematic reviews guidelines, using specific keywords based on the COVID-19 neurological complications described up to May 10th, 2020. Results: A total of 43 articles were selected, including data ranging from common, non-specific symptoms, such as hyposmia and myalgia, to more complex and life-threatening conditions, such as cerebrovascular diseases, encephalopathies, and Guillain-Barré syndrome. Conclusion: Recognition of neurological manifestations of SARS-CoV-2 should be emphasized despite the obvious challenges faced by clinicians caring for critical patients who are often sedated and presenting other concurrent systemic complications.