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Pre-transplant renal functional reserve and renal function after lung transplantation

2020; Elsevier BV; Volume: 39; Issue: 9 Linguagem: Inglês

10.1016/j.healun.2020.05.011

1557-3117

Faeq Husain‐Syed, Fiorenza Ferrari, Horst-Walter Birk, Rolf Weimer, Claudio Ronco, Kevin Poll, Matthias Hecker, Hans-Dieter Walmrath, Werner Seeger, Stefan Kuhnert, Konstantin Mayer,

Organ Transplantation Techniques and Outcomes

Post–lung transplantation (LTx) progressive chronic kidney disease (CKD) is associated with increased morbidity and mortality. 1 Khush KK Cherikh WS Chambers DC et al. The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: thirty-fifth adult heart transplantation report-2018; focus theme: multiorgan transplantation. J Heart Lung Transplant. 2018; 37: 1155-1168 Abstract Full Text Full Text PDF PubMed Scopus (230) Google Scholar Comorbidities and cotreatments and post-LTx medical complications, including acute kidney injury (AKI), are associated with an increased risk for a subsequent CKD development. 2 Fidalgo P Ahmed M Meyer SR et al. Incidence and outcomes of acute kidney injury following orthotopic lung transplantation: a population-based cohort study. Nephrol Dial Transplant. 2014; 29: 1702-1709 Crossref PubMed Scopus (30) Google Scholar However, among the several risk factors for post-LTx CKD development, pre-transplant renal function plays a key role. 3 Osho AA Castleberry AW Snyder LD et al. Determining eligibility for lung transplantation: a nationwide assessment of the cutoff glomerular filtration rate. J Heart Lung Transplant. 2015; 34: 571-579 Abstract Full Text Full Text PDF PubMed Scopus (11) Google Scholar