LASCA-imaging of gene-based speckles: application to detection of the gene polymorphism in a bacterial model
2020; IOP Publishing; Volume: 17; Issue: 6 Linguagem: Inglês
10.1088/1612-202x/ab8b66
ISSN1612-202X
AutoresOnega V. Ulianova, Alexander S. Ulyanov, Sergey Zaytsev, Yury V. Saltykov, Sergey S. Ulyanov, Valentina Feodorova,
Tópico(s)Thermoregulation and physiological responses
ResumoA current trend in modern bioinformatics is representation of nucleotide sequences in the form of gene-based (GB) speckles. In this letter GB-speckles have been processed using the s-LASCA (laser speckle contrast analysis) technique. Statistical properties of s-LASCA images of GB-speckles have been analyzed. It is shown that application of the s-LASCA technique allows us to essentially increase the the sensitivity of detection of a single nucleotide polymorphism using GB-speckles.
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