Can Hypericum perforatum ( SJW ) prevent cytokine storm in COVID ‐19 patients?
2020; Wiley; Volume: 34; Issue: 7 Linguagem: Inglês
10.1002/ptr.6764
ISSN1099-1573
AutoresPellegrino Masiello, Michela Novelli, Pascale Beffy, Marta Menegazzi,
Tópico(s)Sphingolipid Metabolism and Signaling
ResumoPhytotherapy ResearchVolume 34, Issue 7 p. 1471-1473 LETTER TO THE EDITOR Can Hypericum perforatum (SJW) prevent cytokine storm in COVID-19 patients? Pellegrino Masiello, Pellegrino Masiello Department of Translational Research and New Technologies in Medicine and Surgery, School of Medicine, University of Pisa, Pisa, ItalySearch for more papers by this authorMichela Novelli, Michela Novelli Department of Translational Research and New Technologies in Medicine and Surgery, School of Medicine, University of Pisa, Pisa, ItalySearch for more papers by this authorPascale Beffy, Pascale Beffy Institute of Clinical Physiology, CNR, Pisa, ItalySearch for more papers by this authorMarta Menegazzi, Corresponding Author Marta Menegazzi [email protected] orcid.org/0000-0003-1310-9227 Department of Neuroscience, Biomedicine and Movement Sciences, Biochemistry Section, School of Medicine, University of Verona, Verona, Italy Correspondence Marta Menegazzi, Department of Neuroscience, Biomedicine and Movement Sciences, Biochemistry Section, School of Medicine, University of Verona, Strada le Grazie 8, Verona 37134, Italy. Email: [email protected]Search for more papers by this author Pellegrino Masiello, Pellegrino Masiello Department of Translational Research and New Technologies in Medicine and Surgery, School of Medicine, University of Pisa, Pisa, ItalySearch for more papers by this authorMichela Novelli, Michela Novelli Department of Translational Research and New Technologies in Medicine and Surgery, School of Medicine, University of Pisa, Pisa, ItalySearch for more papers by this authorPascale Beffy, Pascale Beffy Institute of Clinical Physiology, CNR, Pisa, ItalySearch for more papers by this authorMarta Menegazzi, Corresponding Author Marta Menegazzi [email protected] orcid.org/0000-0003-1310-9227 Department of Neuroscience, Biomedicine and Movement Sciences, Biochemistry Section, School of Medicine, University of Verona, Verona, Italy Correspondence Marta Menegazzi, Department of Neuroscience, Biomedicine and Movement Sciences, Biochemistry Section, School of Medicine, University of Verona, Strada le Grazie 8, Verona 37134, Italy. Email: [email protected]Search for more papers by this author First published: 05 June 2020 https://doi.org/10.1002/ptr.6764Citations: 12Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat No abstract is available for this article. REFERENCES Albert, D., Zündorf, I., Dingermann, T., Müller, W. E., Steinhilber, D., & Werz, O. (2002). Hyperforin is a dual inhibitor of cyclooxygenase-1 and 5-lipoxygenase. Biochemical Pharmacology, 64(12), 1767–1775. https://doi.org/10.1016/s0006-2952(02)01387-4 10.1016/S0006-2952(02)01387-4 CASPubMedWeb of Science®Google Scholar Biber, A., Fischer, H., Römer, A., & Chatterjee, S. S. (1998). Oral bioavailability of hyperforin from hypericum extracts in rats and human volunteers. Pharmacopsychiatry, 31(Suppl 1), 36–43. https://doi.org/10.1055/s-2007-979344 10.1055/s-2007-979344 CASPubMedWeb of Science®Google Scholar Cui, Y.-H., & Zheng, Y. (2016). A meta-analysis on the efficacy and safety of St John's wort extract in depression therapy in comparison with selective serotonin reuptake inhibitors in adults. Neuropsychiatric Disease and Treatment, 12, 1715–1723. https://doi.org/10.2147/NDT.S106752 10.2147/NDT.S106752 CASPubMedWeb of Science®Google Scholar Dell'Aica, I., Niero, R., Piazza, F., Cabrelle, A., Sartor, L., Colalto, C., … Garbisa, S. (2007). Hyperforin blocks neutrophil activation of matrix metalloproteinase-9, motility and recruitment, and restrains inflammation-triggered angiogenesis and lung fibrosis. The Journal of Pharmacology and Experimental Therapeutics, 321(2), 492–500. https://doi.org/10.1124/jpet.106.116459 10.1124/jpet.106.116459 PubMedWeb of Science®Google Scholar Di Paola, R., Mazzon, E., Muià, C., Crisafulli, C., Genovese, T., Di Bella, P., … Cuzzocrea, S. (2007). Protective effect of Hypericum perforatum in zymosan-induced multiple organ dysfunction syndrome: Relationship to its inhibitory effect on nitric oxide production and its peroxynitrite scavenging activity. Nitric Oxide: Biology and Chemistry, 16(1), 118–130. https://doi.org/10.1016/j.niox.2006.05.006 10.1016/j.niox.2006.05.006 CASPubMedWeb of Science®Google Scholar Febvre-James, M., Bruyère, A., Le Vée, M., & Fardel, O. (2018). The JAK1/2 inhibitor Ruxolitinib reverses Interleukin-6-mediated suppression of drug-detoxifying proteins in cultured human hepatocytes. Drug Metabolism and Disposition: The Biological Fate of Chemicals, 46(2), 131–140. https://doi.org/10.1124/dmd.117.078048 10.1124/dmd.117.078048 CASPubMedWeb of Science®Google Scholar Gobbi, M., Moia, M., Funicello, M., Riva, A., Morazzoni, P., & Mennini, T. (2004). In vitro effects of the dicyclohexylammonium salt of hyperforin on interleukin-6 release in different experimental models. Planta Medica, 70(7), 680–682. https://doi.org/10.1055/s-2004-827194 10.1055/s-2004-827194 CASPubMedWeb of Science®Google Scholar Heinrich, M., Appendino, G., Efferth, T., Fürst, R., Izzo, A. A., Kayser, O., … Viljoen, A. (2020). Best practice in research—Overcoming common challenges in phytopharmacological research. Journal of Ethnopharmacology, 246, 112230. https://doi.org/10.1016/j.jep.2019.112230 10.1016/j.jep.2019.112230 CASPubMedWeb of Science®Google Scholar Levi, M., & van der Poll, T. (2017). Coagulation and sepsis. Thrombosis Research, 149, 38–44. https://doi.org/10.1016/j.thromres.2016.11.007 10.1016/j.thromres.2016.11.007 CASPubMedWeb of Science®Google Scholar Menegazzi, M., Di Paola, R., Mazzon, E., Muià, C., Genovese, T., Crisafulli, C., … Cuzzocrea, S. (2006). Hypericum perforatum attenuates the development of carrageenan-induced lung injury in mice. Free Radical Biology & Medicine, 40(5), 740–753. https://doi.org/10.1016/j.freeradbiomed.2005.08.034 10.1016/j.freeradbiomed.2005.08.034 CASPubMedWeb of Science®Google Scholar Menegazzi, M., Novelli, M., Beffy, P., D'Aleo, V., Tedeschi, E., Lupi, R., … Masiello, P. (2008). Protective effects of St. John's wort extract and its component hyperforin against cytokine-induced cytotoxicity in a pancreatic beta-cell line. The International Journal of Biochemistry & Cell Biology, 40(8), 1509–1521. https://doi.org/10.1016/j.biocel.2007.11.019 10.1016/j.biocel.2007.11.019 CASPubMedWeb of Science®Google Scholar Moore, L. B., Goodwin, B., Jones, S. A., Wisely, G. B., Serabjit-Singh, C. J., Willson, T. M., … Kliewer, S. A. (2000). St. John's wort induces hepatic drug metabolism through activation of the pregnane X receptor. Proceedings of the National Academy of Sciences of the United States of America, 97(13), 7500–7502. https://doi.org/10.1073/pnas.130155097 10.1073/pnas.130155097 CASPubMedWeb of Science®Google Scholar Novelli, M., Beffy, P., Gregorelli, A., Porozov, S., Mascia, F., Vantaggiato, C., … Menegazzi, M. (2019). Persistence of STAT-1 inhibition and induction of cytokine resistance in pancreatic β cells treated with St John's wort and its component hyperforin. The Journal of Pharmacy and Pharmacology, 71(1), 93–103. https://doi.org/10.1111/jphp.12823 10.1111/jphp.12823 CASPubMedWeb of Science®Google Scholar Novelli, M., Beffy, P., Menegazzi, M., De Tata, V., Martino, L., Sgarbossa, A., … Masiello, P. (2014). St. John's wort extract and hyperforin protect rat and human pancreatic islets against cytokine toxicity. Acta Diabetologica, 51(1), 113–121. https://doi.org/10.1007/s00592-013-0518-2 10.1007/s00592-013-0518-2 CASPubMedWeb of Science®Google Scholar Novelli, M., Menegazzi, M., Beffy, P., Porozov, S., Gregorelli, A., Giacopelli, D., … Masiello, P. (2016). St. John's wort extract and hyperforin inhibit multiple phosphorylation steps of cytokine signaling and prevent inflammatory and apoptotic gene induction in pancreatic β cells. The International Journal of Biochemistry & Cell Biology, 81(Pt A), 92–104. https://doi.org/10.1016/j.biocel.2016.10.017 10.1016/j.biocel.2016.10.017 CASPubMedWeb of Science®Google Scholar Zhang, W., Zhao, Y., Zhang, F., Wang, Q., Li, T., Liu, Z., … Zhang, S. (2020). The use of anti-inflammatory drugs in the treatment of people with severe coronavirus disease 2019 (COVID-19): The perspectives of clinical immunologists from China. Clinical Immunology (Orlando, Fla.), 214, 108393. https://doi.org/10.1016/j.clim.2020.108393 10.1016/j.clim.2020.108393 CASPubMedWeb of Science®Google Scholar Citing Literature Volume34, Issue7July 2020Pages 1471-1473 This article also appears in:The Pharmacological Potential of Plant Compounds and Preparations in COVID-19 ReferencesRelatedInformation
Referência(s)