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Artigo Acesso aberto Produção Nacional Revisado por pares
BIBTEX RIS

Patients with COVID-19 and neurological manifestations show undetectable SARS-CoV-2 RNA levels in the cerebrospinal fluid

2020; Elsevier BV; Volume: 96; Linguagem: Inglês

10.1016/j.ijid.2020.05.123

ISSN

1878-3511

Autores

Otávio de Melo Espíndola, Marilda Mendonça Siqueira, Cristiane Soares, Marco Antônio Lima, Ana Claúdia Celestino Bezerra Leite, Abelardo Araújo, Carlos Otávio Brandão, Marcus Tulius T. Silva,

Tópico(s)

Multiple Sclerosis Research Studies

Resumo

We report that patients with COVID-19 displaying distinct neurological disorders have undetectable or extremely low levels of SARS-CoV-2 RNA in the cerebrospinal fluid, indicating that viral clearance precede the neurological involvement. This finding points to the need for the development of more sensitive molecular tests and the investigation of other neurotropic pathogens to exclude concurrent neuroinfection.

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