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Preoperative Irradiation, Lymphadenectomy and 125 Iodine Implant for Patients with Localized Prostatic Carcinoma: a Correlation of Implant Dosimetry with Clinical Results

1980; Lippincott Williams & Wilkins; Volume: 124; Issue: 5 Linguagem: Inglês

10.1016/s0022-5347(17)55593-7

1527-3792

William U. Shipley, Gene Kopelson, Deborah H. Novack, Charlotte Ling, Stephen P. Dretler, George R. Prout,

Advanced Radiotherapy Techniques

No AccessJournal of Urology1 Nov 1980Preoperative Irradiation, Lymphadenectomy and 125Iodine Implant for Patients with Localized Prostatic Carcinoma: a Correlation of Implant Dosimetry with Clinical Results William U. Shipley, Gene Kopelson, Deborah H. Novack, C. Clifton Ling, Stephen P. Dretler, and George R. Prout William U. ShipleyWilliam U. Shipley More articles by this author , Gene KopelsonGene Kopelson More articles by this author , Deborah H. NovackDeborah H. Novack More articles by this author , C. Clifton LingC. Clifton Ling More articles by this author , Stephen P. DretlerStephen P. Dretler More articles by this author , and George R. ProutGeorge R. Prout More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)55593-7AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail The 30 patients with clinically and surgically localized prostatic carcinoma who were selected for treatment by a short course of preoperative irradiation (1,050 rad), pelvic lymphadenectomy and 125iodine implant have been followed for 1 to 4 years. Perioperative morbidity (10 per cent), postimplant impotence (11 per cent), lymphedema (17 per cent), tumor recurrence (4 per cent) and distant metastasis (4 per cent) have been minimal to date. However, urinary irritative symptoms, which usually subsided in 6 to 9 months, occurred in half of the patients and correlated with implant volume. Total dose and total dose per unit of implanted activity were calculated. Of the various implant parameters evaluated implant dose homogeneity has correlated with the rate of tumor regression. © 1980 by The American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetailsCited ByRoss G, Borkon W, Landry L, Marc Edwards F, Weinstein S and Abadir R (2018) Preliminary Observations on the Results of Combined 125Iodine Seed Implantation and External Irradiation for Carcinoma of the ProstateJournal of Urology, VOL. 127, NO. 4, (699-701), Online publication date: 1-Apr-1982.Eugene Carlton C (2018) Editorial CommentJournal of Urology, VOL. 127, NO. 4, (701-701), Online publication date: 1-Apr-1982. Volume 124Issue 5November 1980Page: 639-642 Advertisement Copyright & Permissions© 1980 by The American Urological Association Education and Research, Inc.MetricsAuthor Information William U. Shipley More articles by this author Gene Kopelson More articles by this author Deborah H. Novack More articles by this author C. Clifton Ling More articles by this author Stephen P. Dretler More articles by this author George R. Prout More articles by this author Expand All Advertisement PDF DownloadLoading ...