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Cardiac MRI in Children with Multisystem Inflammatory Syndrome Associated with COVID-19

2020; Radiological Society of North America; Volume: 297; Issue: 3 Linguagem: Inglês

10.1148/radiol.2020202288

1527-1315

Éléonore Blondiaux, Pauline Parisot, Alban Redheuil, Lucile Tzaroukian, Yaël Levy, Chiara Siléo, Aurélie Schnuriger, Mathie Lorrot, Romain Guedj, Hubert Ducou Le Pointe,

Coronary Artery Anomalies

This case series examines cardiac MRI findings in four children and adolescents admitted to intensive care in April 2020 for multisystem inflammatory syndrome and Kawasaki disease–like features related to coronavirus disease 2019 (COVID-19). Acute myocarditis occurred less than 1 week after onset of fever and gastrointestinal symptoms. Physical examination showed rash and cheilitis or conjunctivitis. All patients recovered after intravenous immunoglobulin therapy. Severe acute respiratory syndrome coronavirus 2 reverse transcription polymerase chain reaction was negative in nasopharyngeal, stool, and respiratory samples and was positive on serology. Cardiac MRI showed diffuse myocardial edema on T2 short tau inversion-recovery sequences and native T1 mapping, with no evidence of late gadolinium enhancement suggestive of replacement fibrosis or focal necrosis. These findings favor postinfectious myocarditis in children and adolescents with COVID-19. © RSNA, 2020 Online supplemental material is available for this article.