Scientific Opinion on bluetongue serotype 8
2011; Wiley; Volume: 9; Issue: 5 Linguagem: Inglês
10.2903/j.efsa.2011.2189
ISSN1831-4732
Tópico(s)Viral Infections and Vectors
ResumoEFSA JournalVolume 9, Issue 5 2189 OpinionOpen Access Scientific Opinion on bluetongue serotype 8 EFSA Panel on Animal Health and Welfare, EFSA Panel on Animal Health and WelfareSearch for more papers by this author EFSA Panel on Animal Health and Welfare, EFSA Panel on Animal Health and WelfareSearch for more papers by this author First published: 23 May 2011 https://doi.org/10.2903/j.efsa.2011.2189Citations: 6 Panel members: Philippe Vannier (Chair), Joerg Hartung (Vice-Chair), James Michael Sharp (Vice-Chair), Anette Bøtner, Donald Maurice Broom, Marcus G. Doherr, Mariano Domingo, Linda Keeling, Frank Koenen, Simon More, David Morton, Pascal Oltenacu, Albert Osterhaus, Fulvio Salati, Mo Salman, Moez Sanaa, Jan Arend Stegeman, Endre Szücs, Hans-Hermann Thulke, Anthony John Francis Webster, Martin Wierup Correspondence: AHAW@efsa.europa.eu Acknowledgement: The Panel wishes to thank the members of the Working Group on bluetongue serotype-8: Anette Bøtner, Chris Oura, Claude Saegerman, James MacLachlan, Piet Van Rijn, James Michael Sharp, Jan Arend Stegeman for the preparatory work on this scientific opinion and EFSA staff: Sofie Dhollander, Andrea Gervelmeyer and Diane Lefebvre for the support provided to this scientific opinion. Adoption date: 4 May 2011 Published date: 23 May 2011 Question number: EFSA-Q-2010-01237 On request from: European Commission AboutPDF ToolsExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat Abstract To answer a question from the European Commission on the potential special characteristics of bluetongue virus (BTV) serotype 8 (BTV-8) compared to other serotypes and their possible impact on the epidemiology of the disease, a systematic literature review was carried out by a working group established by the Animal Health and Welfare Panel. Currently, three special features can be assigned to BTV-8, which are the ability to cause serious disease in cattle and goats, the ability to be transmitted transplacentally, and the ability to contaminate semen. The transplacental transmission and the contamination of semen are also observed for several serotypes of modified live virus (MLV) vaccines and for some cell culture/egg passaged strains. These two features may have an impact on the epidemiology of the disease, since they may increase the ability of BTV-8 to survive the winter period, for example, when pregnant cows are infected in late autumn and give birth to viraemic offspring in the next vector season, or, through infecting the recipient dam via artificial insemination (AI) with frozen contaminated semen. Furthermore, the chance of BTV-8 spread may be increased either through movement of seropositive but virus negative pregnant animals, which may give birth to viraemic calves, or through natural mating or AI using BTV-8 contaminated semen by transmission from semen to receiving dam. The current legislation provides effective measures to ensure that all dams are immune to BTV before insemination or mating, so there is no subsequent risk of transplacental infection of their offspring. Furthermore, pregnant animals are effectively restricted in their movement. More research is needed to determine whether oral transmission and/or transmission through embryo transfer are more likely to occur for BTV-8 than for other BTV serotypes. References Akita GY, Glenn J, Castro AE and Osburn BI, 1993. Detection of bluetongue virus in clinical samples by polymerase chain reaction. Journal of Veterinary Diagnostic Investigation, 5, 154– 158. Al Ahmad MZ, Pellerin JL, Larrat M, Chatagnon G, Cécile R, Sailleau C, Zientara S and Fieni F, 2011. Can bluetongue virus (BTV) be transmitted via caprine embryo transfer? Theriogenology. Epub ahead of print, www.ncbi.nlm.nih.gov/pubmed/21397938 DL: 9 May, 2011. Backx A, Heutink CG, van Rooij EMA and van Rijn PA, 2007. Clinical signs of bluetongue virus serotype 8 infection in sheep and goats. Veterinary Record, 161, 591– 593. Backx A, Heutink R, van Rooij E and van Rijn P, 2009. Transplacental and oral transmission of wild-type bluetongue virus serotype 8 in cattle after experimental infection. Veterinary Microbiology, 138, 235– 243. Barber TL, Jochim MM and Osburn BI, 1985. Bluetongue and related orbiviruses ( TL Barber, MM Jochim and BI Osburn, eds). Proceedings First International Symposium, Monterey, California, 16–20 January 1984. A.R. Liss, New York, Progress in Clinical and Biological Research, 178, 746 pp. Barratt-Boyes SM and MacLachlan NJ, 1994. Dynamics of viral spread in bluetongue virus infected calves. Veterinary Microbiology, 40, 361– 371. Batten CA, Maan S, Shaw AE, Maan NS and Mertens PP, 2008. A European field strain of bluetongue virus derived from two parental vaccine strains by genome segment reassortment. Virus Research, 137, 56– 63. Baylis M, O'Connell L and Mellor PS, 2008. Rates of bluetongue virus transmission between Culicoides sonorensis and sheep. Medical and Veterinary Entomology, 22, 228– 237. Belbis G, Gartioux JP, Lagalisse Y, Maillard R, Breard E, Zientara S, and Milleman Y, 2009. Congenital lesions linked to FCO virus in calves from vaccinated mothers. Point Vétérinaire, 40, 295, 67– 71. Bonneau KR, DeMaula CD, Mullens BA and MacLachlan NJ, 2002. Duration of viraemia infectious to Culicoides sonorensis in bluetongue virus-infected cattle and sheep. Veterinary Microbiology, 88, 115– 125. Bowen RA, Howard TH and Pickett BW, 1982. Interaction of bluetongue virus with pre-implantation embryos from mice and cattle. American Journal of Veterinary Research, 43, 1907– 1911. Bowen RA, Howard TH, Elsden RP and Seidel GE, 1983. Embryo transfer from cattle infected with bluetongue virus. American Journal of Veterinary Research, 44, 1625– 1628. Bowen RA and Howard TH, 1984. Transmission of bluetongue virus by intrauterine inoculation or insemination of virus-containing bovine semen. American Journal of Veterinary Research, 45, 1386– 1388. Bowen RA, Howard TH, Elsden RP and Seidel GE, 1985. Bluetongue virus and embryo transfer in cattle. Progress in Clinical Biological Research, 178, 85– 9. Bowne JG, Luedke AJ, Jochim MM and Metcalf HE, 1968. Bluetongue disease in cattle. Journal of American Veterinary Medical Association, 153, 662– 668. Bréard E, Pozzi N, Sailleau C, Durand B, Catinot V, Sellem E, Dumont P, Guerin B and Zientara S, 2007. Transient adverse effects of an attenuated bluetongue virus vaccine on the quality of ram semen. Veterinary Record, 160, 431– 435. Bréard E, Belbis G, Hamers C, Moulin V, Lilin T, Moreau F, Millemann Y, Montange C, Sailleau C, Durand B, Desprat A, Viarouge C, Hoffmann B, de Smit H, Goutebroze S, Hudelet P, and Zientara S, 2011. Evaluation of humoral response and protective efficacy of two inactivated vaccines against bluetongue virus after vaccination of goats. Vaccine, 29, 2495– 2502. Castro AE and Rodgers SJ, 1984. Congenital anomalies in cattle associated with an epizootic of bluetongue virus (serotype II). Bovine Practitioner, 19, 87– 91. Cowley JA and Gorman BM, 1989. Cross-neutralization of genetic reassortants of bluetongue virus serotypes 20 and 21. Veterinary Microbiology, 19, 37– 51. Dal Pozzo F, de Clercq K, Guyot H, Vandemeulebroucke E, Sarradin P, Vandenbussche F, Thiry E and Saegerman C, 2009. Experimental reproduction of bluetongue virus serotype 8 clinical disease in calves. Veterinary Microbiology, 136, 352– 358. Darpel KE, Batten CA, Veronesi E, Shaw AE, Anthony S, Bachanek-Bankowska K, Kgosana L, Bin-Tarif A, Carpenter S, Muller-Doblies UU, Takamatsu HH, Mellor PS, Mertens PP and Oura CA, 2007. Clinical signs and pathology shown by British sheep and cattle infected with bluetongue virus serotype 8 derived from the 2006 outbreak in northern Europe. Veterinary Record, 161, 253– 261. Darpel KE, Batten CA, Veronesi E, Williamson S, Anderson P, Dennison M, Clifford S, Smith C, Philips L, Bidewell C, Bachanek-Bankowska K, Sanders A, Bin-Tarif A, Wilson AJ, Gubbins S, Mertens PP, Oura CA and Mellor PS, 2009. Transplacental transmission of bluetongue virus 8 in cattle, UK. Emerging Infectious Diseases, 15, 2025– 2028. De Clercq K, De Leeuw I, Verheyden B, Vandemeulebroucke E, Vanbinst T, Herr C, Meroc E, Bertels G, Steurbaut N, Miry C, De Bleecker K, Maquet G, Bughin J, Saulmont M, Lebrun M, Sustronck B, De Deken R, Hooyberghs J, Houdart P, Raemaekers M, Mintiens K, Kerkhofs P, Goris N and Vandenbussche F, 2008a. Transplacental infection and apparently immunotolerance induced by a wild-type bluetongue virus serotype 8 natural infection. Transboundry and Emerging Diseases, 55, 352– 359. De Clercq K, Vandenbussche F, Vandemeulebroucke E, Vanbinst T, Leeuw Id, Verheyden B, Goris N, Mintiens K, Meroc E, Herr C, Hooybergs J, Houdart P, Sustronck B, Deken Rd, Maquet G, Bughin J, Saulmont M, Lebrun M, Bertels G and Miry C, 2008b. Transplacental bluetongue infection in cattle. Veterinary Record, 162, 564. de la Concha-Bermejillo A, Schore CE, Dangler CA, Demattos CC, de Mattos CA and Osburn BI, 1992. Comparison of slot blot nucleic acid hybridization, immunofluorescence, and virus isolation techniques to detect bluetongue virus in blood mononuclear cells from cattle with experimentally induced infection. American Journal of Veterinary Research, 53, 2245– 2250. de la Concha-Bermejillo A, Odeon A, BonDurant RH and Osburn BI, 1993. Experimental infection of pregnant cattle with bluetongue virus serotype 11 between postbreeding days 21 and 48. Journal of Veterinary Diagnostic Investigation, 5, 329– 335. Desmecht D, Bergh Rv, Sartelet A, Leclerc M, Mignot C, Misse F, Sudraud C, Berthemin S, Jolly S, Mousset B, Linden A, Coignoul F and Cassart D, 2008. Evidence for transplacental transmission of the current wild-type strain of bluetongue virus serotype 8 in cattle. Veterinary Record, 163, 50– 52. Du Toit RM, 1962. The role played by bovines in the transmission of bluetongue in sheep. Journal of the South African Veterinary Medical Association, 33, 483– 490. EFSA Panel on Animal Health and Welfare (AHAW), 2007a. Scientific Opinion on the EFSA self-mandate on bluetongue origin and occurrence. EFSA Journal, 480, 1– 20. EFSA Panel on Animal Health and Welfare (AHAW), 2007b. Scientific Opinion on bluetongue vectors and vaccines. EFSA Journal, 479, 1– 29. EFSA (European Food Safety Authority), 2007c. Technical report on epidemiological analysis of the 2006 bluetongue virus serotype 8 epidemic in north-western Europe. EFSA Journal, 5(4), 42 pp. EFSA Panel on Animal Health and Welfare (AHAW), 2008a. Scientific Opinion on a request from the European Commission (DG SANCO) on bluetongue. EFSA Journal, 735, 1– 70. EFSA Panel on Animal Health and Welfare (AHAW), 2008b. Scientific Opinion on risk of bluetongue transmission in animal transit. EFSA Journal, 795, 1– 56. EFSA (European Food Safety Authority), 2010. Application of systematic review methodology to food and feed safety assessments to support decision making. EFSA Journal, 8(6), 1637, 90 pp. EFSA Panel on Animal Health and Welfare (AHAW). Scientific Opinion on BTV surveillance and monitoring. In press. Ellis JA, Coen ML, MacLachlan NJ, Wilson WC, Williams ES and Luedke AJ, 1993. Prevalence of bluetongue virus expression in leukocytes from experimentally infected ruminants. American Journal of Veterinary Research, 54, 1452– 1456. Eschbaumer M, Hoffmann B, Moss A, Savini G, Leone A, Konig P, Zemke J, Conraths F and Beer M, 2010a. Emergence of bluetongue virus serotype 6 in Europe-German field data and experimental infection of cattle. Veterinary Microbiology, 143, 189– 195. Eschbaumer M, Wackerlin R, Rudolf M, Keller M, Konig P, Zemke J, Hoffmann B and Beer M, 2010b. Infectious blood or culture-grown virus: A comparison of bluetongue virus challenge models. Veterinary Microbiology, 146, 150– 154. Flanagan M, Wilson AJ, Trueman KF and Shepherd MA, 1982. Bluetongue virus serotype 20 infection in pregnant Merino sheep. Australian Veterinary Journal, 59, 18– 20. Flanagan M and Johnson SJ, 1995. The effects of vaccination of Merino ewes with an attenuated Australian bluetongue virus serotype 23 at different stages of gestation. Australian Veterinary Journal, 72, 455– 457. Forman AJ, Hooper PT and Le Blanc Smith PM, 1989. Pathogenicity for sheep of recent Australian bluetongue virus isolates. Australian Veterinary Journal, 66, 261– 262. Foster NM, Luedke AJ, Parsonson IM and Walton TE, 1991. Temporal relationships of viremia, interferon activity, and antibody responses of sheep infected with several bluetongue virus strains. American Journal of Veterinary Research, 52, 192– 196. Gard GP, Melville LF and Shorthose JE, 1989. Investigations of bluetongue and other arboviruses in the blood and semen of naturally infected bulls. Veterinary Microbiology, 20, 315– 322. Ghalib HW, Cherrington JM and Osburn BI, 1985. Virological, clinical and serological responses of sheep infected with tissue culture adapted bluetongue virus serotypes 10, 11, 13 and 17. Veterinary Microbiology, 10, 179– 188. Gibbs EP, Lawman MJ and Herniman KA, 1979. Preliminary observations on transplacental infection of bluetongue virus in sheep - a possible overwintering mechanism. Research in Veterinary Science, 27, 118– 120. Gibbs P and Greiner EC, 1994. The epidemiology of bluetongue. Comparative Immunology Microbiology and Infectious Diseases, 17, 207– 220. Gillespie JH, Schlafer DH, Foote RH, Quick S, Dougherty E, Schiff E and Allen S, 1990. Comparison of persistence of seven bovine viruses on bovine embryos following in vitro exposure. Deutsche Tierarztliche Wochenschrift, 97, 65– 68. Goldsmit L, Barzilai E and Tadmor A, 1975. The comparative sensitivity of sheep and chicken embryos to bluetongue virus and observations on viraemia in experimentally infected sheep. Australian Veterinary Journal, 51, 190– 196. Groocock CM, Parsonson IM and Campbell CH, 1982. Bluetongue virus serotypes 20 and 17 infections in sheep: comparison of clinical and serological responses. Veterinary Microbiology, 7, 189– 196. Groocock CM, Parsonson IM and Campbell CH, 1983. Bluetongue virus serotype 20 infections in cattle of breeding age. American Journal of Veterinary Research, 44, 1765– 1768. Hamblin C, Salt JS, Graham SD, Hopwood K and Wade-Evans AM, 1998. Bluetongue virus serotypes 1 and 3 infection in Poll Dorset sheep. Australian Veterinary Journal, 76, 622– 629. Hamers C, Galleau S, Chery R, Blanchet M, Besancon L, Cariou C, Werle-Lapostolle B, Hudelet P and Goutebroze S, 2009a. Use of inactivated bluetongue virus serotype 8 vaccine against virulent challenge in sheep and cattle. Veterinary Record, 165, 369– 373. Hamers C, Rehbein S, Hudelet P, Blanchet M, Lapostolle B, Cariou C, Duboeuf M and Goutebroze S, 2009b. Protective duration of immunity of an inactivated bluetongue (BTV) serotype 2 vaccine against a virulent BTV serotype 2 challenge in sheep. Vaccine, 27, 2789– 2793. Hanon JB, Uyttenhoef A, Fecher-Bourgeois F, Kirschvink N, Haubruge E, Duquesne B and Saegerman C, 2009. Quantitative estimation of economical losses linked with the bluetongue (BTV-8) in Walloon Region during the period of 2006–2007. Association pour l'Etude de l'Epidemiologie des Maladies Animales, 56, 187– 195. Hardy WT, and Price DA, 1952. Sore muzzle of sheep. Journal of the American Veterinary Medical Association, 120, 23– 25. Hare WCD, Luedke AJ, Thomas FC, Bowen RA, Singh EL, Eaglesome MD, Randall GCB and Bielanski A, 1988. Nontransmission of bluetongue virus by embryos from bluetongue virus-infected sheep. American Journal of Veterinary Research, 49, 468– 472. Henning MW, 1956. Blue-tongue (Bloutong). Animal diseases in South Africa. Capetown, Central News Agency Ltd. Hutcheon D, 1902. Malarial catarrhal fever of sheep. Veterinary Record, 14, 629– 633. Jeggo MH, Gumm ID and Taylor WP, 1983. Clinical and serological response of sheep to serial challenge with different bluetongue virus types. Research in Veterinary Science, 34, 205– 211. Jochim MM, Luedke AJ and Bowne JG, 1965. The clinical and immunogenic response of sheep to oral and intradermal administrations of bluetongue virus. American Journal of Veterinary Research, 26, 1254– 1260. Johnson SJ, Hoffmann D, Flanagan M, Polkinghorne IG and Bellis GA, 1992. Clinico-pathology of Australian bluetongue virus serotypes for sheep. In: Bluetongue, African horse sickness, and related orbiviruses. Eds TE Walton and BI Osburn. CRC Press, Boca Raton, FL, 737– 743. Katz JB, Gustafson GA, Alstad AD, Adler KA and Moser KM, 1993. Colorimetric diagnosis of prolonged bluetongue viremia in sheep, using an enzyme-linked oligonucleotide sorbent assay of amplified viral nucleic acids. American Journal of Veterinary Research, 54, 2021– 2026. Katz J, Alstad D, Gustafson G and Evermann J, 1994. Diagnostic analysis of the prolonged bluetongue virus RNA presence found in the blood of naturally infected cattle and experimentally infected sheep. Journal of Veterinary Diagnostic Investigation, 6, 139– 142. Kirkbride CA and Johnson MW, 1989. Serologic examination of aborted ovine and bovine fetal fluids for the diagnosis of border disease, bluetongue, bovine viral diarrhea, and leptospiral infections. Journal of Veterinary Diagnostic Investigation, 1, 132– 138. Kirkland PD, Melville LF, Hunt NT, Williams CF and Davis RJ, 2004. Excretion of bluetongue virus in cattle semen: a feature of laboratory-adapted virus. Veterinaria Italiana, 40 497– 501. Koumbati M, Mangana O, Nomikou K, Mellor PS and Papadopoulos O, 1999. Duration of bluetongue viraemia and serological responses in experimentally infected European breeds of sheep and goats. Veterinary Microbiology, 64, 277– 285. Lefèvre PC, Mellor PS and Saegerman C, 2010. Chapter 58: Bluetongue. In: Infectious and Parasitic Disease of Livestock. Lavoisier et Commonwealth Agricultural Bureau-International (ed.), France, 663– 688. Livingston CW, Jr., McConnell S, Cummings G and Gauer BB, 1983. Experimental bluetongue infections in gnotobiotic lambs and kids. American Journal of Veterinary Research, 44, 129– 131. Lopez-Olvera JR, Falconi C, Fernandez-Pacheco P, Fernandez-Pinero J, Sanchez MA, Palma A, Herruzo I, Vicente J, Jimenez-Clavero MA, Arias M, Sanchez-Vizcaino JM and Gortazar C, 2010. Experimental infection of European red deer (Cervus elaphus) with bluetongue virus serotypes 1 and 8. Veterinary Microbiology, 145, 148– 152. Luedke AJ, Jochim MM, Bowne JG and Jones RH, 1970. Observations on latent blue-tongue virus infection in cattle. Journal of the American Veterinary Medical Association, 156, 1871– 1879. Luedke J. Jochim MM and Jones RH, 1977. Bluetongue in cattle: effects of Culicoides variipennis-transmitted bluetongue virus on pregnant heifers and their calves. American Journal of Veterinary Research 38, 1687– 1695. Maan S, Maan NS, Ross-Smith N, Batten CA, Shaw AE, Anthony SJ, Samuel AR, Darpel KE, Veronesi, E, Oura CAL, Singh KP, Nomikou K, Potgieter AC, Attoui H, van Rooij E, van Rijn P, De Clercq K, Vandenbussche F, Zientara S, Bréard E, Sailleau C, Beer M, Hoffman B, Mellor PS and Mertens PPC, 2008. Sequence analysis of bluetongue virus serotype 8 from the Netherlands 2006 and comparison to other European strains. Virology, 377, 308– 318. MacLachlan NJ and Thompson J, 1985. Bluetongue virus-induced interferon in cattle. American Journal of Veterinary Research, 46, 1238– 1241. MacLachlan NJ, Heidner HW and Fuller FJ, 1987. Humoral immune response of calves to bluetongue virus infection. American Journal of Veterinary Research, 48, 1031– 1035. MacLachlan NJ, Jagels G, Rossitto PV, Moore PF and Heidner HW, 1990. The pathogenesis of experimental bluetongue virus infection of calves. Veterinary Pathology, 27, 223– 229. MacLachlan NJ, Nunamaker RA, Katz JB, Sawyer MM, Akita GY, Osburn BI and Tabachnick WJ, 1994. Detection of bluetongue virus in the blood of inoculated calves: comparison of virus isolation, PCR assay, and in vitro feeding of Culicoides variipennis. Archives of Virology, 136, 1– 8. NJ MacLachlan and JE Pearson (eds), 2004. Bluetongue: Proceedings of the 3rd Symposium. Vetineraria Italiana, 40, 1– 730. MacLachlan NJ and Osburn BI, 2006. Impact of bluetongue virus infection on the international movement and trade of ruminants. Journal of the American Veterinary Medical Association, 228, 1346– 1349. MacLachlan NJ, Drew CP, Darpel KE and Worwa G, 2009. The pathology and pathogenesis of bluetongue. Journal of Comparative Pathology, 141, 1– 16. Mahrt CR and Osburn BI, 1986a. Experimental bluetongue virus infection of sheep; effect of previous vaccination: clinical and immunologic studies. American Journal of Veterinary Research, 47, 1191– 1197. Mahrt CR and Osburn BI, 1986b. Experimental bluetongue virus infection of sheep; effect of previous vaccination: pathologic, immunofluorescent and ultrastructural studies. American Journal of Veterinary Research, 47, 1198– 1203. Martinelle L, Dal Pozzo F, Sarradin P, De Leeuw I, De Clercq K, Thys C, Ziant D, Thiry E and Saegerman C, 2011. Two alternative inocula to reproduce bluetongue virus serotype 8 disease in calves. Vaccine, 29, 3600– 3609. Mason JH, and Neitz WO, 1940. The susceptibility of cattle to the virus of bluetongue. Onderstepoort Journal of Veterinary Research, 15, 145– 157. Mayo CE, Crossley BM, Hietala SK, Gardner IA, Breitmeyer RE and MacLachlan NJ, 2010. Colostral transmission of bluetongue virus nucleic acid among newborn dairy calves in California. Transboundary and Emerging Diseases, 57, 277– 281. McColl KA and Gould AR, 1994. Bluetongue virus infection in sheep: haematological changes and detection by polymerase chain reaction. Australian Veterinary Journal, 71, 97– 101. McKercher DG, Saito JK and Singh KV, 1970. Serologic evidence of an etiologic role for bluetongue virus in hydranencephaly of calves. Journal of American Veterinary Medical Association, 156, 1044– 1047. Menzies FD, McCullough SJ, McKeown IM, Forster JL, Jess S, Batten C, Murchie AK, Gloster J, Fallows JG, Pelgrim W, Mellor PS and Oura CAL, 2008. Evidence for transplacental and contact transmission of bluetongue virus in cattle. Veterinary Record, 163, 203– 209. Mertens PP, Pedley S, Cowley J, Burroughs JN, Corteyn AH, Jeggo MH, Jennings DM and Gorman BM, 1989. Analysis of the roles of bluetongue virus outer capsid proteins VP2 and VP5 in determination of virus serotype. Virology, 170, 561– 565. Metcalf HE, Pearson JE and Klingsporn AL, 1981. Bluetongue in cattle: a serological survey of slaughter cattle in the United States. American Journal of Veterinary Research, 42, 1057– 1061. Monaco F, Bonfini B, Zaghini M, Antonucci D, Pini A and Savini G, 2004a. Vaccination of cattle using monovalent modified-live vaccine against bluetongue virus serotype 2: innocuity, immunogenicity and effect on pregnancy. Veterinaria Italiana, 40, 671– 675. Monaco F, Luca ND, Spina P, Morelli D, Liberatore I, Citarella R, Conte A and Savini G, 2004b. Virological and serological response of cattle following field vaccination with bivalent modified-live vaccine against bluetongue virus serotypes 2 and 9. Veterinaria Italiana, 40, 657– 660. Moulton JE, 1961. Pathology of bluetongue in sheep in California. Journal of the American Vetinerary Medical Association, 138, 493– 498. Nevill EM, 1971. Cattle and Culicoides biting midges as possible overwintering hosts of bluetongue virus. Onderstepoort Journal of Veterinary Research, 38, 65– 72. Osburn BI, McGowan B, Heron B, Loomis B, Bushnell R, Stott J and Utterback W, 1981. Epizootiologic study of bluetongue: virologic and serologic results. American Journal of Veterinary Research, 42, 884– 887. Owen NC, Du Toit RM and Howell PG, 1965. Bluetongue in cattle: typing of viruses isolated from cattle exposed to natural infections. Onderstepoort Journal of Veterinary Research, 32, 3– 6. Parsonson IM, Della-Porta AJ and Snowdon WA, 1981a. Developmental disorders of the fetus in some arthropod-borne virus infections. American Journal of Tropical Medicine and Hygiene, 30, 600– 673. Parsonson IM, Della-Porta AJ, McPhee DA, Cybinski DH, Squire KRE, Standfast HA and Uren MF, 1981b. Isolation of bluetongue virus serotype 20 from the semen of an experimentally-infected bull. Australian Veterinary Journal, 57, 252– 253. Parsonson IM, Della-Porta AJ, McPhee DA, Cybinski DH, Squire KR and Uren MF, 1987a. Experimental infection of bulls and cows with bluetongue virus serotype 20. Australian Veterinary Journal, 64, 10– 13. Parsonson IM, Della-Porta AJ, McPhee DA, Cybinski DH, Squire KR and Uren MF, 1987b. Bluetongue virus serotype 20: experimental infection of pregnant heifers. Australian Veterinary Journal, 64, 14– 17. Parsonson IM, Luedke AJ, Barber TL and Walton TE, 1994. Bluetongue virus infection in pregnant ewes. American Journal of Veterinary Research, 55, 666– 669. Parsonson IM and McColl KA, 1995. Retrospective diagnosis of bluetongue virus in stored frozen and fixed tissue samples using PCR. Veterinary Microbiology, 46, 143– 149. Peters M, Mosenfechtel S, Jacobsen B, Beineke A and Wohlsein P, 2008. Bluetongue virus serotype 8 (BTV-8)-associated brain malformations in two calves. Deutsche Tierarztliche Wochenschrift, 115, 298– 303. Phillips RM, Carnahan DL and Rademacher DJ, 1986. Virus isolation from semen of bulls serologically positive for bluetongue virus. American Journal of Veterinary Research, 47, 84– 85. Pierce CM, Balasuriya UB and MacLachlan NJ, 1998, Phylogenetic analysis of the S10 gene of field and laboratory strains of bluetongue virus from the United States. Virus Research, 55, 15– 27. Pini A, 1976. Study on the pathogenesis of bluetongue: replication of the virus in the organs of infected sheep. Onderstepoort Journal of Veterinary Research, 43, 159– 164. Potgieter AC, Monaco F, Mangana O, Nomikou K, Yadin H and Savini G, 2005. VP2-segment sequence analysis of some isolates of bluetongue virus recovered in the Mediterranean Basin during the 1998–2003 outbreak. Journal of Veterinary Medicine, 52, 372– 379. Ramig RF, Garrison C, Chen D and Bell-Robinson D, 1989. Analysis of reassortment and superinfection during mixed infection of Vero cells with bluetongue virus serotypes 10 and 17. Journal of General Virology, 70, 2595– 2603. Richards RG, MacLachlan NJ, Heidner HW and Fuller FJ, 1988. Comparison of virologic and serologic responses of lambs and calves infected with bluetongue virus serotype 10. Veterinary Microbiology, 18, 233– 242. Richardson C, Taylor WP, Terlecki S and Gibbs EP, 1985. Observations on transplacental infection with bluetongue virus in sheep. American Journal of Veterinary Research, 46, 1912– 1922. Roeder PL, Taylor WP, Roberts DH, Wood L, Jeggo MH, Gard GP, Corteyn M and Graham S, 1991. Failure to establish congenital bluetongue virus infection by infecting cows in early pregnancy. Veterinary Record, 128, 301– 304. Saegerman C and Pastoret PP, 2009. Bluetongue in northern Europe: appearance of new serotypes within an enzootic ground. Bulletin de l'OIE, 1, 35– 39. Saegerman C, Bolkaerts B, Baricalla C, Raes M, Wiggers L, de Leeuw I, Vandenbussche F, Zimmer JY, Haubruge E, Cassart D, De Clercq K and Kirschvink N, 2011. The impact of naturally-occurring, trans-placental bluetongue virus serotype-8 on reproductive performance in sheep. Veterinary Journal, 187, 72– 80. Samal SK, El-Hussein A, Holbrook FR, Beaty BJ and Ramig RF, 1987a. Mixed infection of Culicoides variipennis with bluetongue virus serotypes 10 and 17: evidence for high frequency reassortment in the vector. Journal of General Virology, 68, 2319– 2329. Samal SK, Livingston CW,
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