High-throughput dynamic BH3 profiling may quickly and accurately predict effective therapies in solid tumors
2020; American Association for the Advancement of Science; Volume: 13; Issue: 636 Linguagem: Inglês
10.1126/scisignal.aay1451
ISSN1937-9145
AutoresPatrick Bhola, Eman Y. Ahmed, Jennifer L. Guerriero, Ewa Sicińska, Emily Su, Elizaveta Lavrova, Jing Ni, Otari Chipashvili, Timothy Hagan, Marissa S. Pioso, Kelley E. McQueeney, Kimmie Ng, Andrew J. Aguirre, James M. Cleary, David Cocozziello, Alaba Sotayo, Jeremy Ryan, Jean J. Zhao, Anthony Letai,
Tópico(s)PARP inhibition in cancer therapy
ResumoEffective treatments might be identified by rapidly profiling drug sensitivities in patient biopsies from solid tumors.
Referência(s)