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Design, development, testing at ISO standards and in vivo feasibility study of a novel polymeric heart valve prosthesis

2020; Royal Society of Chemistry; Volume: 8; Issue: 16 Linguagem: Inglês

10.1039/d0bm00412j

2047-4849

Joanna Stasiak, Marta Serrani, Eugenia Biral, James V. Taylor, Azfar Zaman, Samantha Jones, Thomas Ness, Francesco De Gaetano, Maria Laura Costantino, Vito Domenico Bruno, M.Saadeh Suleiman, Raimondo Ascione, Geoff D. Moggridge,

Mechanical Circulatory Support Devices

A novel polymeric heart valve shows durability equivalent to 25 years in accelerated bench testing, in vitro hydrodynamics equivalent to existing bioprosthetic valves; and good performance in a small acute feasibility study in sheep.