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Characteristics and Outcome of Children with Renal Cell Carcinoma: A Narrative Review

2020; Multidisciplinary Digital Publishing Institute; Volume: 12; Issue: 7 Linguagem: Inglês

10.3390/cancers12071776

2072-6694

Justine N. van der Beek, James I. Geller, Ronald R. de Krijger, Norbert Graf, Kathy Pritchard‐Jones, Jarno Drost, Arnauld Verschuur, Dermot Murphy, Satyajit Ray, Filippo Spreafico, Kristina Dzhuma, Annemieke S. Littooij, Barbara Selle, Godelieve A.M. Tytgat, Marry M. van den Heuvel‐Eibrink,

Pancreatic and Hepatic Oncology Research

Pediatric renal cell carcinoma (RCC) is a rare type of kidney cancer, most commonly occurring in teenagers and young adolescents. Few relatively large series of pediatric RCC have been reported. Knowledge of clinical characteristics, outcome and treatment strategies are often based on the more frequently occurring adult types of RCC. However, published pediatric data suggest that clinical, molecular and histological characteristics of pediatric RCC differ from adult RCC. This paper summarizes reported series consisting of ≥10 RCC pediatric patients in order to create an up-to-date overview of the clinical and histopathological characteristics, treatment and outcome of pediatric RCC patients.