Portal de Periódicos da CAPES

Similarities between COVID-19 and anti-MDA5 syndrome: what can we learn for better care?

2020; European Respiratory Society; Volume: 56; Issue: 3 Linguagem: Inglês

10.1183/13993003.01618-2020

1399-3003

Margherita Giannini, Mickaël Ohana, Benoît Nespola, Giovanni Zanframundo, Bernard Gény, Alain Meyer,

Inflammatory Myopathies and Dermatomyositis

As yet, no direct-acting antiviral drugs have demonstrated efficacy in the disease. In contrast, increasing evidence indicates an immune-mediated pathophysiology that is paving the way for the evaluation of immunomodulation strategies [2]. In support of this view, we would like to highlight the striking similarities between COVID-19 and a rare autoimmune disease: the anti-MDA5-syndrome. Similarities between COVID-19 and anti-MDA5 syndrome support further evaluation of employing an immunomodulatory strategy in COVID-19 We thank Pragnell Babette for her English support.