The value of genotypic and imaging information to predict functional and structural outcomes in ADPKD
2020; American Society for Clinical Investigation; Volume: 5; Issue: 15 Linguagem: Inglês
10.1172/jci.insight.138724
ISSN2379-3708
AutoresSravanthi Lavu, Lisa E. Vaughan, Sarah R. Senum, Timothy L. Kline, Arlene B. Chapman, Ronald D. Perrone, Michal Mrug, William E. Braun, Theodore I. Steinman, Frederic F. Rahbari-Oskoui, Godela Brosnahan, Kyongtae T. Bae, Douglas Landsittel, Fouad T. Chebib, Alan S.L. Yu, Vicente E. Torres, Peter C. Harris,
Tópico(s)Biomedical Research and Pathophysiology
ResumoBACKGROUND. A treatment option for autosomal dominant polycystic kidney disease (ADPKD) has highlighted the need to identify rapidly progressive patients. Kidney size/age and genotype have predictive power for renal outcomes, but their relative and additive value, plus associated trajectories of disease progression, are not well defined.
Referência(s)