Artigo Acesso aberto Revisado por pares

Interferon-γ signaling in human iPSC–derived neurons recapitulates neurodevelopmental disorder phenotypes

2020; American Association for the Advancement of Science; Volume: 6; Issue: 34 Linguagem: Inglês

10.1126/sciadv.aay9506

ISSN

2375-2548

Autores

Katherine Warre‐Cornish, Leo Perfect, Roland Nagy, Rodrigo R. R. Duarte, Matthew J. Reid, Pooja Raval, Annett Mueller, Amanda Evans, Amalie C.M. Couch, Cédric Ghevaert, Gráinne McAlonan, Eva Loth, Declan Murphy, Timothy R. Powell, Anthony C. Vernon, Deepak P. Srivastava, Jack Price,

Tópico(s)

Neuroinflammation and Neurodegeneration Mechanisms

Resumo

Interferon-γ induces cellular and transcriptomic changes in human neural cells associated with neurodevelopmental disorders.

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