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The effect of a pre- and post-operative exercise programme versus standard care on physical fitness of patients with oesophageal and gastric cancer undergoing neoadjuvant treatment prior to surgery (The PERIOP-OG Trial): Study protocol for a randomised controlled trial

2020; Springer Science+Business Media; Volume: 21; Issue: 1 Linguagem: Inglês

10.1186/s13063-020-04311-4

1745-6215

Róisín Tully, Lisa Loughney, Jarlath Bolger, Jan Sørensen, O. J. McAnena, Chris Collins, Paul Carroll, Mayilone Arumugasamy, Tomas J. Murphy, William B. Robb, Wendy Hickey, Claire Coleman, Louise Buckley, Eileen Lombard, Noel McCaffrey, Pamela Gallagher, Claire Timon, Patricia M. Kearney, Aoife Quinn, Emma Houlihan, David O'Dwyer, Catherine Woods, Raymond G. O'Connor, Sinéad Kelly, Bróna Kehoe, Mark McManus, Austin Twomey,

Gastric Cancer Management and Outcomes

Advances in peri-operative oncological treatment, surgery and peri-operative care have improved survival for patients with oesophagogastric cancers. Neoadjuvant cancer treatment (NCT) reduces physical fitness, which may reduce both compliance and tolerance of NCT as well as compromising post-operative outcomes. This is particularly detrimental in a patient group where malnutrition is common and surgery is demanding. The aim of this trial is to assess the effect on physical fitness and clinical outcomes of a comprehensive exercise training programme in patients undergoing NCT and surgical resection for oesophagogastric malignancies.