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Personalized Therapy Approach for Hospitalized Patients with Coronavirus Disease 2019

2020; Oxford University Press; Volume: 74; Issue: 1 Linguagem: Inglês

10.1093/cid/ciaa964

1537-6591

Carolina García‐Vidal, Estela Moreno-García, Marta Hernández‐Meneses, Pedro Puerta‐Alcalde, Mariana Chumbita, Nicole García-Pouton, Laura Linares, Verónica Rico, Celia Cardozo, José Antonio Martínez, Felipe García, Josep Mensa, Pedro Castro, José M. Nicolás, José Muñóz, David González Vidal, Álex Soriano, Marta Bodro, Laura Morata, Juan Ambrosioni, Daiana Agüero, Berta Torres, Ana González-Cordón, Lorena de la Mora, Laura Linares, Fernanda Meira, Irene Macaya, Natalia Hernández Rodríguez, David Nicolás, Laia Albiach, Alex Almuedo-Riera, Ma Ángeles Marcos, Ma Ángeles Marcos, Mariana Fernández-Pittol, Berta Fidalgo, Daniel Camprubí, Catia Cillóniz, Antoní Torres, Adrián Téllez, Sara Fernández, Gemma Sanjuan, Pau Cano, David Caellas,

SARS-CoV-2 and COVID-19 Research

Abstract Hospitalized patients with coronavirus disease 2019 (COVID-19) experiencing respiratory symptoms have different complications (inflammatory, co-infection, and thrombotic) that are identifiable by analytics patterns. Personalized treatment decisions decreased early mortality (odds ratio [OR] .144; 95% confidence interval [CI] .03–.686; P = .015). Increasing age (OR 1.06; P = .038) and therapeutic effort limitation (OR 9.684; P < .001) were associated with higher mortality.