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A PET Prototype for “In-Beam” Monitoring of Proton Therapy

2009; Institute of Electrical and Electronics Engineers; Volume: 56; Issue: 1 Linguagem: Inglês

10.1109/tns.2008.2008306

1558-1578

Sara Del Vecchio, Francesca Attanasi, Nicola Belcari, M. Camarda, G.A.P. Cirrone, G. Cuttone, F. Di Rosa, Nico Lanconelli, Sascha Moehrs, V. Rosso, G. Russo, A. Del Guerra,

Nuclear Physics and Applications

The in-beam PET is a novel PET application to image the $\beta^{+}$ activity induced in biological tissues by hadronic therapeutic beams. Thanks to the correlation existing between beam-delivered dose profiles and beam-induced activity profiles, in vivo information about the effective ion paths can be extracted from the in-beam PET image. In-situ measurements, immediately after patient irradiation, are recommended in order to exploit the maximum statistics, by also detecting the contribution provided by the very short lived isotopes, e.g. $^{15}{\rm O}$ . A compact, dedicated tomograph should then be developed for such an application, so as to be used in the treatment room.