Portal de Periódicos da CAPES

Use of Dual-Layered Stents for Carotid Artery Angioplasty

2020; Elsevier BV; Volume: 13; Issue: 14 Linguagem: Inglês

10.1016/j.jcin.2020.03.048

1936-8798

Eugenio Stabile, Gianmarco de Donato, Piotr Musiałek, Koen Deloose, Roberto Nerla, Pasqualino Sirignano, Adam Mazurek, Wassim Mansour, Vincenzo Fioretti, Fabrizio Esposito, Salvatore Chianese, Marc Bosiers, Carlo Setacci, Francesco Speziale, Antonio Micari, Giovanni Esposito,

Intracranial Aneurysms: Treatment and Complications

This study sought to evaluate 1-year safety and efficacy of dual-layered mesh-covered carotid stent systems (DLS) for carotid artery stenting (CAS). Small clinical studies evaluating 1-year outcomes of CAS performed with 2 available DLS, Roadsaver (RS) (Terumo Corp., Tokyo, Japan) and CGuard (CG) (InspireMD, Boston, Massachusetts), have been published. The authors performed an individual patient–level meta-analysis including studies enrolling more than 100 CAS with DLS. The primary endpoint was the death and stroke rate; secondary endpoints were restenosis and in-stent thrombosis rates at 1 year. Patients were divided into 2 groups according to DLS (RS n = 250; CG n = 306). At 1 year, 11 patients died (1.97%), 7 patients in the group RS (2.8%) and 4 patients in the CG one (1.31%); and 10 strokes occurred, 4 in the group RS (1.6%) and 6 in the CG one (1.96%). Overall death and stroke rate was 3.77% (n = 21), 11 events in the group RS group (4.4%) and 10 in the CG group (3.27%). Symptomatic status was the only predictor of death and or stroke. At 1 year, restenosis occurred in 12 patients (2.1%), 10 in the group RS (4%) and 2 in the CG one (0.65%) (p = 0.007). In-stent thrombosis occurred in 1 patient (0.18%) in the CG group (0.32%). RS use was the only independent predictor of restenosis. This study suggests that DLS use for CAS is associated with a low 1-year death and stroke rate, and the specific DLS stent used could affect the restenosis rate.