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Influence of immunosuppression on seroconversion against SARS‐CoV‐2 in two kidney transplant recipients

2020; Wiley; Volume: 23; Issue: 1 Linguagem: Inglês

10.1111/tid.13423

1399-3062

Aileen X. Wang, Orlando Quintero, Dora Y. Ho, Stéphan Busque, Colin R. Lenihan,

SARS-CoV-2 detection and testing

Solid organ transplant recipients are at risk for infectious complications due to chronic immunosuppression. The outbreak of coronavirus disease 2019 (COVID-19) in the United States has raised growing concerns for the transplant patient population. We seek to add to the current limited literature on COVID-19 in transplant recipients by describing the clinical course of two kidney transplant recipients with SARS-CoV-2 infection monitored by both RT-PCR and serology. Through careful adjustment of their immunosuppression regimen, both patients had excellent recovery with intact graft function and development of anti-SARS-CoV-2 antibodies.