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Incidental finding of COVID-19 infection after [68Ga]Ga-PSMA-11 PET/CT imaging in a patient with prostate cancer

2020; Springer Science+Business Media; Volume: 48; Issue: 2 Linguagem: Inglês

10.1007/s00259-020-04932-6

ISSN

1619-7089

Autores

Camila Edith Stachera Stasiak, Fabrícius Rocha Cardoso, Sérgio Altino de Almeida, Paulo Henrique Rosado-de-Castro,

Tópico(s)

Radiopharmaceutical Chemistry and Applications

Resumo

In Brazil, the first COVID-19 case was confirmed on February 26, 2020, and by May 26, 2020, the number of confirmed cases was of 391,222, with 24,512 confirmed deaths [1].CT and [ 18 F]FDG PET/CT findings in COVID-19 have been described in several reports [2,3], but to our knowledge findings in [ 68 Ga]-labeled radiopharmaceuticals PET/CT remain to be described.An asymptomatic 66-year-old man from Rio de Janeiro underwent [ 68 Ga]Ga-PSMA-11 PET/CT on March 20, 2020, requesting for primary staging of prostate cancer.The patient denied any history of foreign travel.Prior biopsy showed a Gleason score of 8 (4 + 4) and the PSA level was 21.6 ng/ml.PET/CT identified two foci with [ 68 Ga]Ga-PSMA-11 uptake in an enlarged prostate, one in the right prostate lobe in the transition zone (SUVmax 23.5) and other in the prostate basis (SUVmax 16.9).No other radiotracer uptake related to the primary disease was present (a, MIP image).However, peripheral ground-glass opacities in superior and inferior lobes of both lungs were identified on CT (b-d, axial CT; green arrows), presenting mild radiopharmaceutical uptake with an SUVmax of 2.5 (e, f, axial PET/CT; h, i, axial PET; red

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