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BIBTEX RIS

Increased PIP3 activity blocks nanoparticle mRNA delivery

2020; American Association for the Advancement of Science; Volume: 6; Issue: 30 Linguagem: Inglês

10.1126/sciadv.aba5672

ISSN

2375-2548

Autores

Kalina Paunovska, Alejandro Da Silva Sanchez, Matthew T. Foster, David Loughrey, Emmeline L. Blanchard, Fatima Z. Islam, Zubao Gan, Athanasios Mantalaris, Philip J. Santangelo, James E. Dahlman,

Tópico(s)

RNA and protein synthesis mechanisms

Resumo

PIP3, a bioactive lipid upstream of the PI3K/AKT/mTOR pathway, decreased protein translated from nanoparticle-delivered mRNA.

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