Cell identity and nucleo-mitochondrial genetic context modulate OXPHOS performance and determine somatic heteroplasmy dynamics
2020; American Association for the Advancement of Science; Volume: 6; Issue: 31 Linguagem: Inglês
10.1126/sciadv.aba5345
ISSN2375-2548
AutoresAna Victoria Lechuga‐Vieco, Ana Latorre, Iain G. Johnston, Gennaro Prota, Uzi Gileadi, Raquel Justo‐Méndez, Rebeca Acín‐Pérez, Raquel Martínez de Mena, Jose María Fernández-Toro, Daniel Jiménez-Blasco, Alfonso Mora, José Ángel Nicolás-Ávila, Demetrio J. Santiago, Silvia G. Priori, Juan P. Bolaños, Guadalupe Sabio, Luis M. Criado, Jesús Ruíz‐Cabello, Vincenzo Cerundolo, Nick S. Jones, José Antonio Enrı́quez,
Tópico(s)Physiological and biochemical adaptations
ResumoCells sense the presence of more than one version of mtDNA and select the variant according to its impact on function.
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