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A multicenter study on epidemiological and clinical characteristics of 125 newborns born to women infected with COVID-19 by Turkish Neonatal Society

2020; Springer Science+Business Media; Volume: 180; Issue: 3 Linguagem: Inglês

10.1007/s00431-020-03767-5

1432-1076

Mehmet Yekta Öncel, İlke Mungan Akın, Mehmet Kenan Kanburoğlu, Cüneyt Tayman, Şenay Coşkun, Fatma Narter, İlkay Er, Tinatin Gelenava Oncan, Aslı Memişoğlu, Merih Çetınkaya, Demet Oğuz, Ömer Erdeve, Esin Koç, Turan Derme, Dilek Şahın, Bülent Güzel, Arzu Bilge Tekin, Yasemin Akın, Ahmet Kale, Hüseyin Aktürk, Mehmet Özsürmeli, Nazife Reyyan Gök, Rabia Merve Palalıoğlu, Abdurrahman Hamdi İnan, Hülya Özdemir, Esra Eşim Büyükbayrak, İbrahim Polat, Gülser Bingöl Dikdere, Leyla Bilgin, Tuğba Saraç Sivrikoz, İbrahim Caner, Hilal Uslu Yuvacı, Nursu Kara, Ali Galip Zebitay, Emel Okulu, Erkan Kalafat, Nurdan Uraş, Bülent Tekin, Nükhet Aladağ Çiftdemir, Muhammet Bulut, Ali Bülbül, Nilüfer Okur, Ferda Özlü, Kadir Şerafettin Tekgündüz, Adil Umut Zübarioğlu, Hüseyin Altunhan, Baran Cengiz Arcagök, Canan Aygün, Nihat Demir, İsmail Kürşat Gökçe, Nazlı Dilay Gültekin, Handan Hakyemez Toptan, Ferit Kulalı, Sinan Tüfekçi, Funda Tüzün, Akan Yaman, Hüseyin Üstün,

Maternal and fetal healthcare

Limited data are available on pregnant women with COVID-19 and their neonates. We aimed to evaluate the epidemiological and clinical characteristics of newborns born to women infected with COVID-19. A multicenter cohort study was conducted among newborns born to mothers with COVID-19 in 34 neonatal intensive care units (NICUs) in Turkey. Pregnant women (n = 125) who had a positive RT-PCR test and their newborns were enrolled. Cesarean section, prematurity, and low-birthweight infant rates were 71.2%, 26.4%, and 12.8%, respectively. Eight of 125 mothers (6.4%) were admitted to an intensive care unit for mechanical ventilation, among whom six died (4.8%). Majority of the newborns (86.4%) were followed in isolation rooms in the NICU. Four of 120 newborns (3.3%) had a positive RT-PCR test result. Although samples taken on the first day were negative, one neonate became positive on the second day and the other two on the fifth day. Sample from deep tracheal aspirate was positive on the first day in an intubated case. Conclusion: COVID-19 in pregnant women has important impacts on perinatal and neonatal outcomes. Maternal mortality, higher rates of preterm birth and cesarean section, suspected risk of vertical transmission, and low rate of breastfeeding show that family support should be a part of the care in the NICU. Trial registration: ClinicalTrials.gov identifier: NCT04401540