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Progress from Alzheimer's tangles to pathological tau points towards more effective therapies now

2006; IOS Press; Volume: 9; Issue: s3 Linguagem: Inglês

10.3233/jad-2006-9s328

1875-8908

Virginia M.‐Y. Lee, John Q. Trojanowski,

Computational Drug Discovery Methods

The landmark description of neurofibrillary tangles (NFTs) and senile plaques as the pathological hallmarks of an unusual form of dementia 100 years ago by Alois Alzheimer launched the quest to understand a neurodegenerative disorder that now has bec