Artigo Acesso aberto Revisado por pares

Identification of Monohexosylceramides From Euglena gracilis by Electrospray Ionization Mass Spectrometry

2020; SAGE Publishing; Volume: 15; Issue: 8 Linguagem: Inglês

10.1177/1934578x20942351

ISSN

1934-578X

Autores

Nairui Zhang, Kanae Kohama, Miyuki Miyagawa, Moe Mansho, Ryota Sugimoto, Ayaka Nakashima, Kengo Suzuki, Hiroshi Kitagaki,

Tópico(s)

Carbohydrate Chemistry and Synthesis

Resumo

To date, the monohexosylceramides present in the eukaryotic alga Euglena gracilis has not been reported. In this study, we extracted and purified a lipid fraction that eluted similarly to other reported monohexosylceramides. The structural determination of the lipid fraction revealed a monohexosylceramide ( m/ z = 889.5 and a loss of m/ z = 162), corresponding to the formula C 54 H 99 O 8 N having moieties corresponding to a monohexose (C 6 H 12 O 6 ), a 9-methyl-4,8-sphingadienine (C 19 H 37 O 2 N), and a nonacosanoic acid with 2 double bonds (C 29 H 54 O 2 ). This is the first report of the isolation of monohexosylceramides from E. gracilis and will promote its utilization in functional foods and cosmetics.

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