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NG-Circos: next-generation Circos for data visualization and interpretation

2020; Oxford University Press; Volume: 2; Issue: 3 Linguagem: Inglês

10.1093/nargab/lqaa069

2631-9268

Ya Cui, Zhe Cui, Jianfeng Xu, Dapeng Hao, Jiejun Shi, Dan Wang, Hui Xiao, Xiaohong Duan, Runsheng Chen, Wei Li,

Gene expression and cancer classification

Abstract Circos plots are widely used to display multi-dimensional next-generation genomic data, but existing implementations of Circos are not interactive with limited support of data types. Here, we developed next-generation Circos (NG-Circos), a flexible JavaScript-based circular genome visualization tool for designing highly interactive Circos plots using 21 functional modules with various data types. To our knowledge, NG-Circos is the most powerful software to construct interactive Circos plots. By supporting diverse data types in a dynamic browser interface, NG-Circos will accelerate the next-generation data visualization and interpretation, thus promoting the reproducible research in biomedical sciences and beyond. NG-Circos is available at https://wlcb.oit.uci.edu/NG-Circos and https://github.com/YaCui/NG-Circos.