Portal de Periódicos da CAPES

Platelets Can Associate With SARS-CoV-2 RNA and Are Hyperactivated in COVID-19

2020; Lippincott Williams & Wilkins; Volume: 127; Issue: 11 Linguagem: Inglês

10.1161/circresaha.120.317703

1524-4571

Younes Zaid, Florian Puhm, Isabelle Allaeys, Abdallah Naya, Mounia Oudghiri, Loubna Khalki, Youness Limami, Nabil Zaïd, Khalid Sadki, Rafiqua Ben El Haj, Wissal Mahir, Lamiae Belayachi, Bouchra Belefquih, A. Benouda, Amine Cheikh, Marc‐André Langlois, Yahia Cherrah, Louis Flamand, Fadila Guessous, Éric Boilard,

Dermatological and COVID-19 studies

In addition to the overwhelming lung inflammation that prevails in COVID-19, hypercoagulation and thrombosis contribute to the lethality of subjects infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Platelets are chiefly implicated in thrombosis. Moreover, they can interact with viruses and are an important source of inflammatory mediators. While a lower platelet count is associated with severity and mortality, little is known about platelet function during COVID-19.