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Artigo Acesso aberto Produção Nacional Revisado por pares
BIBTEX RIS

Hemorrhagic stroke and COVID-19 infection: Coincidence or causality?

2020; Elsevier BV; Volume: 21; Linguagem: Inglês

10.1016/j.ensci.2020.100274

ISSN

2405-6502

Autores

Pedro Henrique Almeida Fraiman, Mariana Freire, Manuel Moreira Neto, Clécio Godeiro‐Júnior,

Tópico(s)

Alzheimer's disease research and treatments

Resumo

Amyloid Protein Precursor gene duplication is a rare cause of early-onset Alzheimer's disease that can be associated with Cerebral Amyloid Angiopathy. This condition predisposes cerebrovascular events, specifically, intracerebral hemorrhagic stroke. This report describes a case of first-time intracerebral hemorrhage in a patient with APP gene duplication during SARS-CoV-2 infection, a typically pro-thrombotic and pro-inflammatory condition, as a possible trigger for this condition.

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