Produção Nacional
Revisado por pares
Dementia in Latin America: Paving the way toward a regional action plan
2020; Wiley; Volume: 17; Issue: 2 Linguagem: Inglês
10.1002/alz.12202
ISSN1552-5279
AutoresMario A. Parra, Sandra Báez, Lucas Sedeño, Cecilia González Campo, Hernando Santamaría‐García, Ivan Aprahamian, Paulo Henrique Ferreira Bertolucci, Julián Bustin, Maria Aparecida Camargos Bicalho, Carlos Cano, Paulo Caramelli, Márcia Lorena Fagundes Chaves, Patricia Cogram, Bárbara Costa Beber, Felipe A. Court, Leonardo Cruz de Souza, Nilton Custodio, Andrés Damián, Myriam De la Cruz Puebla, Roberta Diehl Rodriguez, Sônia Maria Dozzi Brucki, Laís Fajersztajn, Gonzalo Farías, Fernanda G. De Felice, Raffaele Ferrari, Fabricio Ferreira de Oliveira, Sérgio T. Ferreira, Renata Eloah de Lucena Ferretti‐Rebustini, Márcio Luiz Figueredo Balthazar, Norberto Anízio Ferreira Frota, Patricio Fuentes, Adolfo M. García, Patricia García, Fábio Henrique de Gobbi Porto, Lissette Duque Peñailillo, Henry Engler, Irene Maier, Ignácio F. Mata, Christian González‐Billault, Oscar L. López, Laura Morelli, Ricardo Nitríni, Yakeel T. Quiroz, Alejandra Guerrero Barragán, David Huepe, Fabricio Joao Pio, Cláudia Kimie Suemoto, Renata Kochhann, Silvia Kochen, Fiona Kumfor, Serggio Lanata, Bruce L. Miller, Letı́cia Lessa Mansur, Mirna Lie Hosogi, Patricia Lillo, Jorge Llibre Guerra, David Lira, Francisco Lopera, Adelina Comas, José Alberto Ávila‐Funes, Ana Luisa Sosa, Cláudia Ramos, Elisa de Paula França Resende, Heather M. Snyder, Ioannis Tarnanas, Jenifer Yokoyama, Juan Llibre, Juan F. Cardona, Kate L Possin, Kenneth S. Kosik, Rosa Montesinos, Sebastián Moguilner, Patricia Cristina Lourdes Solis, Renata Eloah de Lucena Ferretti‐Rebustini, Jeronimo Martin Ramirez, Diana Matallana, Lingani Mbakile‐Mahlanza, Alyne Mendonça Marques Ton, Ronnielly Melo Tavares, Eliane Correa Miotto, Graciela Muñiz‐Terrera, Luis Arnoldo Muñoz‐Nevárez, David Orozco, Maira Okada de Oliveira, Olivier Piguet, Maritza Pintado Caipa, Stefanie Danielle Piña‐Escudero, Lucas Porcello Schilling, André Luiz Rodrigues Palmeira, Mônica Sanches Yassuda, José Manuel Santacruz Escudero, Rodrigo Bernardo Serafim, Jerusa Smid, Andrea Slachevsky, Cecília Serrano, Marcio Soto‐Añari, Leonel Tadao Takada, Lea T. Grinberg, Antônio Lúcio Teixeira, Maira Tonidandel Barbosa, Dominic Trepél, Agustín Ibáñez,
Tópico(s)Health Systems, Economic Evaluations, Quality of Life
ResumoAbstract Across Latin American and Caribbean countries (LACs), the fight against dementia faces pressing challenges, such as heterogeneity, diversity, political instability, and socioeconomic disparities. These can be addressed more effectively in a collaborative setting that fosters open exchange of knowledge. In this work, the Latin American and Caribbean Consortium on Dementia (LAC‐CD) proposes an agenda for integration to deliver a Knowledge to Action Framework (KtAF). First, we summarize evidence‐based strategies (epidemiology, genetics, biomarkers, clinical trials, nonpharmacological interventions, networking, and translational research) and align them to current global strategies to translate regional knowledge into transformative actions. Then we characterize key sources of complexity (genetic isolates, admixture in populations, environmental factors, and barriers to effective interventions), map them to the above challenges, and provide the basic mosaics of knowledge toward a KtAF. Finally, we describe strategies supporting the knowledge creation stage that underpins the translational impact of KtAF.
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